Dynamics of dendritic spines in the mouse auditory cortex during memory formation and memory recall

…, M Peter, L Ushakova, T Wernle… - Proceedings of the …, 2013 - National Acad Sciences
Long-lasting changes in synaptic connections induced by relevant experiences are believed
to represent the physical correlate of memories. Here, we combined chronic in vivo two-…

Correlation structure of grid cells is preserved during sleep

RJ Gardner, L Lu, T Wernle, MB Moser, EI Moser - Nature neuroscience, 2019 - nature.com
The network of grid cells in the medial entorhinal cortex (MEC) forms a fixed reference frame
for mapping physical space. The mechanistic origin of the grid representation is unknown, …

Integration of grid maps in merged environments

T Wernle, T Waaga, M Mørreaunet, A Treves… - Nature …, 2018 - nature.com
… To estimate if the change in residual mean square roots in A|B versus AB was significant,
we applied a Student’s t test to the squared residuals before versus after wall removal. …

Induction of immediate early genes in the mouse auditory cortex after auditory cued fear conditioning to complex sounds

…, TR Burkard, J Tinter, T Wernle… - Genes, Brain and …, 2012 - Wiley Online Library
Immediate early genes (IEGs) are widely used as markers to delineate neuronal circuits
because they show fast and transient expression induced by various behavioral paradigms. In …

[HTML][HTML] Increased H3K9me3 and F-Actin Reorganization in the Rapid Adaptive Response to Hypergravity in Human T Lymphocytes

K Wernlé, CS Thiel, O Ullrich - International Journal of Molecular Sciences, 2023 - mdpi.com
… In this study, we subjected human Jurkat T-lymphocytes to different hypergravity states
within a fixed-angle centrifuge. Histone modifications H3K4me3 and H3K9me3 and the nuclear …

Cortical and subcortical blood flow effects of subthalamic nucleus stimulation in PD

T Hershey, FJ Revilla, AR Wernle, L McGee-Minnich… - Neurology, 2003 - AAN Enterprises
… SPM99 assigned a t-value to each voxel in the brain and examined the t-map for voxels that
exceeded a height threshold (t = 4.84; corrected p < 0.05). The program identified clusters of …

Stimulation of STN impairs aspects of cognitive control in PD

T Hershey, FJ Revilla, A Wernle, PS Gibson… - Neurology, 2004 - AAN Enterprises
Objective: To test the hypothesis that subthalamic nucleus (STN) stimulation in Parkinson
disease (PD) patients affects working memory and response inhibition performance, …

[HTML][HTML] 26th annual computational neuroscience meeting (CNS* 2017): part 1

…, T Nowotny, D Han, S Hong, S Rosay, T Wernle… - BMC …, 2017 - Springer
… , these models still fail to account for some of the experimental results, in particular how two
distinct grid patterns are integrated when two compartments are merged into one (Wernle et …

Subthalamic nucleus stimulation-induced regional blood flow responses correlate with improvement of motor signs in Parkinson disease

…, J Wu, JWM Usche, FJ Revilla, JM Hartlein, AR Wernle… - Brain, 2008 - academic.oup.com
… OFF and ON scans with paired t-tests to reveal significant … A t-value was assigned to each
voxel in the brain, and the t-map was examined for voxels that exceeded a height threshold (t = …

Local irradiation alters bone morphology and increases bone fragility in a mouse model

JD Wernle, TA Damron, MJ Allen, KA Mann - Journal of biomechanics, 2010 - Elsevier
Insufficiency fracture following radiation therapy (RTx) is a challenging clinical problem and
typical bone mass measures fail to predict these fractures. The goals of this research were to …