User profiles for T.-Y. Dora Tang
 | TY Dora TangMPI-CBG Verified email at mpi-cbg.de Cited by 2547 |
Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model
Mechanisms of prebiotic compartmentalization are central to providing insights into how
protocellular systems emerged on the early Earth. Protocell models are based predominantly on …
protocellular systems emerged on the early Earth. Protocell models are based predominantly on …
MaxSynBio: avenues towards creating cells from the bottom up
A large German research consortium mainly within the Max Planck Society (“MaxSynBio”)
was formed to investigate living systems from a fundamental perspective. The research …
was formed to investigate living systems from a fundamental perspective. The research …
[HTML][HTML] Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning
It has long been proposed that phase-separated compartments can provide a basis for the
formation of cellular precursors in prebiotic environments. However, we know very little about …
formation of cellular precursors in prebiotic environments. However, we know very little about …
Reversible pH‐responsive coacervate formation in lipid vesicles activates dormant enzymatic reactions
In situ, reversible coacervate formation within lipid vesicles represents a key step in the
development of responsive synthetic cellular models. Herein, we exploit the pH responsiveness …
development of responsive synthetic cellular models. Herein, we exploit the pH responsiveness …
[HTML][HTML] In vitro gene expression within membrane-free coacervate protocells
TYD Tang, D Van Swaay, A DeMello… - Chemical …, 2015 - pubs.rsc.org
… Tang a , Dirk van Swaay b , Andrew deMello b , JL Ross Anderson c and Stephen Mann
* a … TYD Tang, M. Antognozzi, JA Vicary, AW Perriman and S. Mann, Soft Matter, 2013, 9 …
* a … TYD Tang, M. Antognozzi, JA Vicary, AW Perriman and S. Mann, Soft Matter, 2013, 9 …
[HTML][HTML] Non-equilibrium conditions inside rock pores drive fission, maintenance and selection of coacervate protocells
Key requirements for the first cells on Earth include the ability to compartmentalize and evolve.
Compartmentalization spatially localizes biomolecules from a dilute pool and an evolving …
Compartmentalization spatially localizes biomolecules from a dilute pool and an evolving …
Microfluidic formation of membrane‐free aqueous coacervate droplets in water
We report on the formation of coacervate droplets from poly(diallyldimethylammonium chloride)
with either adenosine triphosphate or carboxymethyl‐dextran using a microfluidic flow‐…
with either adenosine triphosphate or carboxymethyl‐dextran using a microfluidic flow‐…
Small-molecule uptake in membrane-free peptide/nucleotide protocells
TYD Tang, M Antognozzi, JA Vicary, AW Perriman… - Soft Matter, 2013 - pubs.rsc.org
The spontaneous phase separation of peptide/nucleotide droplets in water produces
membrane-free chemically organized micro-compartments that offer new opportunities for the …
membrane-free chemically organized micro-compartments that offer new opportunities for the …
[PDF][PDF] Microfluidic tools for bottom-up synthetic cellularity
Microfluidic tools and technologies offer an engineering methodology for the bottom-up
synthesis of artificial cells. Herein, we discuss how droplet-based microfluidic systems may be …
synthesis of artificial cells. Herein, we discuss how droplet-based microfluidic systems may be …
[HTML][HTML] Microfluidic formation of proteinosomes
Herein we describe a novel microfluidic method for the generation of proteinosome micro-droplets,
based on bovine serum albumin and glucose oxidase conjugated to PNIPAAm chains…
based on bovine serum albumin and glucose oxidase conjugated to PNIPAAm chains…