The density of mitotic figures (MF) within tumor tissue is known to be highly correlated with
tumor proliferation and thus is an important marker in tumor grading. Recognition of MF by …

… Polymerase chain reaction products of the expected size from all cases were purified and
cloned by using the TOPO TA cloning kit. c Sequencing reactions were performed by using the …

The prognostic value of mitotic figures in tumor tissue is well-established for many tumor
types and automating this task is of high research interest. However, especially deep learning-…

Canine mammary carcinoma (CMC) has been used as a model to investigate the pathogenesis
of human breast cancer and the same grading scheme is commonly used to assess …

Standardization of tumor assessment lays the foundation for validation of grading systems,
permits reproducibility of oncologic studies among investigators, and increases confidence in …

Equine herpesvirus 9 was detected in a polar bear with progressive encephalitis; the source
was traced to 2 members of a potential equid reservoir species, Grevy’s zebras. The virus …

Counting mitotic figures (MF) in hematoxylin and eosin–stained histologic sections is an
integral part of the diagnostic pathologist’s tumor evaluation. The mitotic count (MC) is used …

The mitotic count (MC) is an important histological parameter for prognostication of malignant
neoplasms. However, it has inter- and intraobserver discrepancies due to difficulties in …

Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient
outcome assessment. This task is challenging for algorithms and human experts alike, with …

A 12-year-old female polar bear (Ursus maritimus) developed a sudden onset of muscle
tremors, erratic circling, increased blinking, head shaking, and ptyalism, which progressed to …