User profiles for TC Boothby
Thomas C. BoothbyUniversity of Wyoming Verified email at uwyo.edu Cited by 1437 |
[HTML][HTML] The biology of tardigrade disordered proteins in extreme stress tolerance
C Hesgrove, TC Boothby - Cell Communication and Signaling, 2020 - Springer
… Boothby, Unpublished). Additionally, incubation of co-solutes with CAHS and other IDPs
results in mixtures that form vitrified solids with dramatically different thermal properties (Boothby…
results in mixtures that form vitrified solids with dramatically different thermal properties (Boothby…
Intrinsically disordered proteins and desiccation tolerance: elucidating functional and mechanistic underpinnings of anhydrobiosis
TC Boothby, GJ Pielak - BioEssays, 2017 - Wiley Online Library
Over 300 years ago the father of microscopy, Antonie van Leeuwenhoek, observed dried
rotifers (tiny animals) “coming back to life” upon rehydration. Since then, scientists have been …
rotifers (tiny animals) “coming back to life” upon rehydration. Since then, scientists have been …
[PDF][PDF] Tardigrades use intrinsically disordered proteins to survive desiccation
… Boothby et al. show that tardigrade disordered proteins are required for desiccation tolerance
and exogenously protect cells and purified enzymes from drying. When dry, these proteins …
and exogenously protect cells and purified enzymes from drying. When dry, these proteins …
Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade
TC Boothby, JR Tenlen, FW Smith… - Proceedings of the …, 2015 - National Acad Sciences
Horizontal gene transfer (HGT), or the transfer of genes between species, has been recognized
recently as more pervasive than previously suspected. Here, we report evidence for an …
recently as more pervasive than previously suspected. Here, we report evidence for an …
[HTML][HTML] Mechanisms and evolution of resistance to environmental extremes in animals
TC Boothby - EvoDevo, 2019 - Springer
… Photo credit: Boothby. e Depiction of the shorthorn sculpin, am arctic fish that utilizes type I
antifreeze proteins to prevent internal ice formation under freezing temperatures. Image credit…
antifreeze proteins to prevent internal ice formation under freezing temperatures. Image credit…
[PDF][PDF] Removal of retained introns regulates translation in the rapidly developing gametophyte of Marsilea vestita
TC Boothby, RS Zipper, CM van der Weele… - Developmental cell, 2013 - cell.com
The utilization of stored RNA is a driving force in rapid development. Here, we show that
retention and subsequent removal of introns from pre-mRNAs regulate temporal patterns of …
retention and subsequent removal of introns from pre-mRNAs regulate temporal patterns of …
[PDF][PDF] The compact body plan of tardigrades evolved by the loss of a large body region
The superphylum Panarthropoda (Arthropoda, Onychophora, and Tardigrada) exhibits a
remarkable diversity of segment morphologies, enabling these animals to occupy diverse …
remarkable diversity of segment morphologies, enabling these animals to occupy diverse …
[HTML][HTML] Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance
…, S Kc, T Gonzalez, H Tapia, TC Boothby - Communications …, 2022 - nature.com
… Silvia Sanchez Martinez and Shahar Sukenik as well as members of the Boothby Lab for
discussions and reading of this manuscript. We thank members of the Water and Life Interface …
discussions and reading of this manuscript. We thank members of the Water and Life Interface …
LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching
…, KN Schaefer, JK Heppert, TC Boothby… - Journal of Cell …, 2018 - rupress.org
… Author contributions: TC Fadero and PS Maddox codesigned and assembled all LITE
prototypes, including the final … TC Boothby maintained, fixed, and stained H. dujardini cultures. …
prototypes, including the final … TC Boothby maintained, fixed, and stained H. dujardini cultures. …
[HTML][HTML] Production of reactive oxygen species and involvement of bioprotectants during anhydrobiosis in the tardigrade Paramacrobiotus spatialis
Water unavailability is an abiotic stress causing unfavourable conditions for life. Nevertheless,
some animals evolved anhydrobiosis, a strategy allowing for the reversible organism …
some animals evolved anhydrobiosis, a strategy allowing for the reversible organism …