User profiles for TO. Metz

Tom Metz

Pacific Northwest National Laboratory
Verified email at pnnl.gov
Cited by 17444

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

…, M Litaudon, JL Wolfender, JE Kyle, TO Metz… - Nature …, 2016 - nature.com
… obtain the best experience, we recommend you use a more up to date browser (or turn off
to the addition of genome annotations to GenBank 9 . To create a robust library, we have to

A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease

…, RD Smith, JW Baynes, TO Metz - Journal of proteome …, 2009 - ACS Publications
… These metrics are regularly updated to reflect usage leading up to the last few days. …
the formation of the Amadori product, it is common today to refer to glycation of proteins by …

[HTML][HTML] Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation

…, WJ Qian, BJM Webb-Robertson, TO Metz - Nature protocols, 2021 - nature.com
… obtain the best experience, we recommend you use a more up to date browser … to verification
to validation phases 22,23] . This transition requires a different set of quality assessments to

[PDF][PDF] Human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice

…, E Borenstein, JK Jansson, R Knight, TO Metz… - Cell, 2019 - cell.com
to explore the contribution of the microbiota to ASD etiology, we sought to define functional
contributions by the gut microbiota to … with ASD was sufficient to promote core behavioral …

[HTML][HTML] Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics

…, MA Gritsenko, Q Zhang, R Zhao, TO Metz… - PLoS …, 2010 - journals.plos.org
to a fresh tube and the volume of sample was reduced to ∼… was then added to reduce the
amount of TFE in the samples to <10… However, we would like to emphasize that it is not clear to

[HTML][HTML] Dengue virus infection perturbs lipid homeostasis in infected mosquito cells

…, RJ Moore, KW Weitz, L Pasa-Tolic, TO Metz… - PLoS …, 2012 - journals.plos.org
… Utilizing a fluorescent PC substrate (BODIPY-PC) we used mass spectrometry to monitor
the hydrolysis of PC to LPC by intracellular PLA 2 . Essentially, we monitored the production of …

[HTML][HTML] Effect of genetic diagnosis on patients with previously undiagnosed disease

…, J Loscalzo, X Luo, AT McCray, TO Metz… - … England Journal of …, 2018 - Mass Medical Soc
… We evaluated patients who were referred to the UDN … to the storage and sharing of information
and biologic materials, the ability to travel to a clinical site for evaluation or availability to

Review, evaluation, and discussion of the challenges of missing value imputation for mass spectrometry-based label-free global proteomics

…, RD Smith, KD Rodland, TO Metz… - Journal of proteome …, 2015 - ACS Publications
… We then apply selected imputation strategies to three label-free LC–MS datasets to evaluate
the accuracy with respect to metrics of variance and sample classification. We examine …

[HTML][HTML] Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

…, D Petras, A Shade, J Stegen, SJ Song, TO Metz… - Nature …, 2022 - nature.com
… obtain the best experience, we recommend you use a more up to date … to further generalize
our findings to those habitats. Similarly, we hope to expand sampling geographically to

Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury

…, J Chang, L Aicher, KM Waters, RD Smith, TO Metz… - MBio, 2013 - Am Soc Microbiol
… with host signaling and expression networks to mediate disease severity. In this study,
we have developed an unbiased modeling approach to identify new pathways and network …