Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor

P Georgiou, P Zanos, TCM Mou, X An… - Nature …, 2022 - nature.com
We show that the sex of human experimenters affects mouse behaviors and responses following
administration of the rapid-acting antidepressant ketamine and its bioactive metabolite (…

[HTML][HTML] Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders

TCM Mou, MV Lane, DDC Ireland, D Verthelyi… - Neurobiology of …, 2022 - Elsevier
An early inflammatory insult is the most recognized risk factor associated with neurodevelopmental
psychiatric disorders, even more so than genetic variants. Notably, complement …

Quantitative analysis of kynurenine aminotransferase II in the adult rat brain reveals high expression in proliferative zones and corpus callosum

…, CN Vaughn, JD Nicholson, KJ Murphy, TCM Mou… - Neuroscience, 2018 - Elsevier
Kynurenic acid, a metabolite of the kynurenine pathway of tryptophan degradation, acts as
an endogenous antagonist of alpha7 nicotinic and NMDA receptors and is implicated in a …

[HTML][HTML] Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity

X Fu, AP Shah, J Keighron, TCM Mou… - Translational …, 2021 - nature.com
Despite the high prevalence of obesity, little is known about its potential impact on the
pharmacokinetics of psychotropic drugs. In the course of investigating the role of the microRNA …

Experimenter sex modulates mouse biobehavioural and pharmacological responses

P Georgiou, P Zanos, TCM Mou, X An, DM Gerhard… - BioRxiv, 2022 - biorxiv.org
Differential rodent responses to the sex of human experimenters could have far reaching
consequences in preclinical studies. Here, we show that the sex of human experimenters …

Neuroinflammatory Signatures of Complement Component 4 in the Subventricular Zone of Autism Spectrum Disorder and Schizophrenia

TCM Mou, MV Lane, DDC Ireland, LH Tonelli… - 2022 - archive.hshsl.umaryland.edu
In addition to an early inflammatory insult, genetic variants that impinge upon immune
function are among the most recognized risk factors associated with neurodevelopmental …

Estradiol mediates stress-susceptibility in the male brain

P Georgiou, TCM Mou, LE Potter, X An, P Zanos… - bioRxiv, 2022 - biorxiv.org
In susceptible populations, stress is a major risk factor for the development of mental disorders,
including depression. Estradiol, often considered a female hormone, is distributed in the …

Constitutive deletion of translin (Tsn) enhances locomotor response to amphetamine: role of developmental effects

…, TCM Mou, B Ladenheim, J Alt, D Fukudome, M Niwa… - bioRxiv, 2020 - biorxiv.org
The translin/trax microRNA-degrading enzyme mediates activity-induced changes in
translation that underlie several long-lasting forms of cellular plasticity. As translin and trax are …

[BOOK][B] Estimating the Q-matrix for cognitive diagnosis models in a Bayesian framework

M Chung - 2014 - search.proquest.com
This research aims to develop an MCMC algorithm for estimating the Q-matrix in a Bayesian
framework. A saturated multinomial model was used to estimate correlated attributes in the …

Wang Ch'ung's Anti-Confucian Struggle

C Ta - Chinese Studies in Philosophy, 1976 - Taylor & Francis
… Lying and not looking the horse in the mouth, he replied that he wanted to implement his
political ideas and also blatantly announced: I'm no gourd; I can't just go through the …