User profiles for Tadakimi Tomita
Tadakimi TomitaAlbert Einstein College of Medicine Verified email at einstein.yu.edu Cited by 959 |
[HTML][HTML] Secreted Effectors Modulating Immune Responses to Toxoplasma gondii
T Tomita, RB Guevara, LM Shah, AY Afrifa, LM Weiss - Life, 2021 - mdpi.com
Toxoplasma gondii is an obligate intracellular parasite that chronically infects a third of
humans. It can cause life-threatening encephalitis in immune-compromised individuals. …
humans. It can cause life-threatening encephalitis in immune-compromised individuals. …
Type II Toxoplasma gondii KU80 Knockout Strains Enable Functional Analysis of Genes Required for Cyst Development and Latent Infection
BA Fox, A Falla, LM Rommereim, T Tomita… - Eukaryotic …, 2011 - Am Soc Microbiol
Type II Toxoplasma gondii KU80 knockouts (Δku80) deficient in nonhomologous end joining
were developed to delete the dominant pathway mediating random integration of targeting …
were developed to delete the dominant pathway mediating random integration of targeting …
[HTML][HTML] The Toxoplasma gondii Cyst Wall Protein CST1 Is Critical for Cyst Wall Integrity and Promotes Bradyzoite Persistence
T Tomita, DJ Bzik, YF Ma, BA Fox, LM Markillie… - PLoS …, 2013 - journals.plos.org
Toxoplasma gondii infects up to one third of the world's population. A key to the success of T.
gondii as a parasite is its ability to persist for the life of its host as bradyzoites within tissue …
gondii as a parasite is its ability to persist for the life of its host as bradyzoites within tissue …
Enrichment and Proteomic Characterization of the Cyst Wall from In Vitro Toxoplasma gondii Cysts
V Tu, J Mayoral, T Sugi, T Tomita, B Han, YF Ma… - MBio, 2019 - Am Soc Microbiol
The tissue cyst of Toxoplasma gondii , found in latent infection, serves a critical role in both
transmission and reactivation of this organism. Within infected cells, slowly replicating …
transmission and reactivation of this organism. Within infected cells, slowly replicating …
Microsporidia interact with host cell mitochondria via voltage-dependent anion channels using sporoplasm surface protein 1
B Han, Y Ma, V Tu, T Tomita, J Mayoral, T Williams… - MBio, 2019 - Am Soc Microbiol
Microsporidia are opportunistic intracellular pathogens that can infect a wide variety of hosts
ranging from invertebrates to vertebrates. During invasion, the microsporidian polar tube …
ranging from invertebrates to vertebrates. During invasion, the microsporidian polar tube …
Toxoplasma gondii Requires Glycogen Phosphorylase for Balancing Amylopectin Storage and for Efficient Production of Brain Cysts
T Sugi, V Tu, Y Ma, T Tomita, LM Weiss - MBio, 2017 - Am Soc Microbiol
In immunocompromised hosts, latent infection with Toxoplasma gondii can reactivate from
tissue cysts, leading to encephalitis. A characteristic of T. gondii bradyzoites in tissue cysts is …
tissue cysts, leading to encephalitis. A characteristic of T. gondii bradyzoites in tissue cysts is …
Making Home Sweet and Sturdy: Toxoplasma gondii ppGalNAc-Ts Glycosylate in Hierarchical Order and Confer Cyst Wall Rigidity
T Tomita, T Sugi, R Yakubu, V Tu, Y Ma, LM Weiss - MBio, 2017 - Am Soc Microbiol
The protozoan intracellular parasite Toxoplasma gondii forms latent cysts in the central
nervous system (CNS) and persists for the lifetime of the host. This cyst is cloaked with a …
nervous system (CNS) and persists for the lifetime of the host. This cyst is cloaked with a …
Toxoplasma gondii cyclic AMP-dependent protein kinase subunit 3 is involved in the switch from tachyzoite to bradyzoite development
T Sugi, YF Ma, T Tomita, F Murakoshi, MS Eaton… - MBio, 2016 - Am Soc Microbiol
Toxoplasma gondii is an obligate intracellular apicomplexan parasite that infects warm-blooded
vertebrates, including humans. Asexual reproduction in T. gondii allows it to switch …
vertebrates, including humans. Asexual reproduction in T. gondii allows it to switch …
Dense Granule Protein GRA64 Interacts with Host Cell ESCRT Proteins during Toxoplasma gondii Infection
The intracellular parasite Toxoplasma gondii adapts to diverse host cell environments within
a replicative compartment that is heavily decorated by secreted proteins. In an attempt to …
a replicative compartment that is heavily decorated by secreted proteins. In an attempt to …
Toxoplasma gondii matrix antigen 1 is a secreted immunomodulatory effector
T Tomita, D Mukhopadhyay, B Han, R Yakubu, V Tu… - Mbio, 2021 - Am Soc Microbiol
Our studies on novel cyst wall proteins serendipitously led us to the discovery that cyst wall
and vacuolar matrix protein MAG1, first identified a quarter of a century ago, functions as a …
and vacuolar matrix protein MAG1, first identified a quarter of a century ago, functions as a …