User profiles for Takahiro Deguchi

Takahiro Deguchi

EMBL (The European Molecular Biology Laboratory)
Verified email at embl.de
Cited by 886

Direct observation of motor protein stepping in living cells using MINFLUX

T Deguchi, MK Iwanski, EM Schentarra, C Heidebrecht… - Science, 2023 - science.org
Dynamic measurements of molecular machines can provide invaluable insights into their
mechanism, but these measurements have been challenging in living cells. Here, we …

Quantum-confined stark effect in an AlGaN/GaN/AlGaN single quantum well structure

TDT Deguchi, KSK Sekiguchi… - Japanese journal of …, 1999 - iopscience.iop.org
Excitonic absorption was observed in a transmittance spectrum of AlGaN/GaN/AlGaN single
quantum well structure with a well width of 5 nm at room temperature. The total internal …

A robust and versatile platform for image scanning microscopy enabling super-resolution FLIM

M Castello, G Tortarolo, M Buttafava, T Deguchi… - Nature …, 2019 - nature.com
Image scanning microscopy (ISM) can improve the effective spatial resolution of confocal
microscopy to its theoretical limit. However, current implementations are not robust or versatile, …

[HTML][HTML] Fourier ring correlation simplifies image restoration in fluorescence microscopy

S Koho, G Tortarolo, M Castello, T Deguchi… - Nature …, 2019 - nature.com
Fourier ring correlation (FRC) has recently gained popularity among fluorescence microscopists
as a straightforward and objective method to measure the effective image resolution. …

Ratiometric sensing and imaging of intracellular pH using polyethylenimine-coated photon upconversion nanoprobes

T Nareoja, T Deguchi, S Christ, R Peltomaa… - Analytical …, 2017 - ACS Publications
Measurement of changes of pH at various intracellular compartments has potential to solve
questions concerning the processing of endocytosed material, regulation of the acidification …

[HTML][HTML] c-Src/Cav1-dependent activation of the EGFR by Dsg2

…, F Cooper, DM Brennan-Crispi, T Deguchi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The desmosomal cadherin, desmoglein 2 (Dsg2), is deregulated in a variety of human
cancers including those of the skin. When ectopically expressed in the epidermis of transgenic …

Pixel reassignment in image scanning microscopy: a re-evaluation

CJR Sheppard, M Castello, G Tortarolo, T Deguchi… - JOSA A, 2020 - opg.optica.org
Image scanning microscopy is a technique based on confocal microscopy, in which the
confocal pinhole is replaced by a detector array, and the resulting image is reconstructed, …

Functionalization of graphene oxide nanostructures improves photoluminescence and facilitates their use as optical probes in preclinical imaging

…, DŞ Karaman, SA Burikov, TA Dolenko, T Deguchi… - Nanoscale, 2015 - pubs.rsc.org
Recently reported photoluminescent nanographene oxides (nGOs), ie nanographene oxidised
with a sulfuric/nitric acid mixture (SNOx method), have tuneable photoluminescence and …

Orientation and aggregation of cationic laser dyes in a fluoromica: polarized spectrometry studies

N Iyi, R Sasai, T Fujita, T Deguchi, T Sota… - Applied Clay …, 2002 - Elsevier
Polarized infrared (IR) and polarized ultraviolet–visible light (UV–VIS) absorption spectra were
measured for cationic laser dyes, rhodamine 6G (R6G) and oxazine 4 (Ox4), incorporated …

STED‐TEM correlative microscopy leveraging nanodiamonds as intracellular dual‐contrast markers

N Prabhakar, M Peurla, S Koho, T Deguchi, T Näreoja… - Small, 2018 - Wiley Online Library
Abstract Development of fluorescent and electron dense markers is essential for the
implementation of correlative light and electron microscopy, as dual‐contrast landmarks are …