User profiles for Takahiro Kikawada

Takahiro Kikawada

Univ. Tokyo; National Agriculture and Food Research Organization (NARO)
Verified email at affrc.go.jp
Cited by 3641

Vitrification is essential for anhydrobiosis in an African chironomid, Polypedilum vanderplanki

…, D Tanaka, Y Nakahara, T Kikawada… - Proceedings of the …, 2008 - National Acad Sciences
Anhydrobiosis is an extremely dehydrated state in which organisms show no detectable
metabolism but retain the ability to revive after rehydration. Thus far, two hypotheses have been …

Dehydration-induced expression of LEA proteins in an anhydrobiotic chironomid

T Kikawada, Y Nakahara, Y Kanamori, K Iwata… - Biochemical and …, 2006 - Elsevier
Late embryogenesis abundant (LEA) proteins are associated with desiccation tolerance in
anhydrobiotic organisms. The larvae of an African chironomid, Polypedilum vanderplanki, are …

Trehalose transporter 1, a facilitated and high-capacity trehalose transporter, allows exogenous trehalose uptake into cells

T Kikawada, A Saito, Y Kanamori… - Proceedings of the …, 2007 - National Acad Sciences
Trehalose is potentially a useful cryo- or anhydroprotectant molecule for cells and
biomolecules such as proteins and nucleotides. A major obstacle to application is that cellular …

Radiation tolerance in the tardigrade Milnesium tardigradum

…, C Katagiri, M Watanabe, T Kikawada… - … journal of radiation …, 2006 - Taylor & Francis
Purpose: Tardigrades are known to survive high doses of ionizing radiation. However, there
have been no reports about radiation effects in tardigrades under culture conditions. In this …

[HTML][HTML] Comparative genome sequencing reveals genomic signature of extreme desiccation tolerance in the anhydrobiotic midge

…, M Hasebe, T Okuda, N Satoh, T Kikawada - Nature …, 2014 - nature.com
Anhydrobiosis represents an extreme example of tolerance adaptation to water loss, where
an organism can survive in an ametabolic state until water returns. Here we report the first …

Desiccation-induced structuralization and glass formation of group 3 late embryogenesis abundant protein model peptides

T Shimizu, Y Kanamori, T Furuki, T Kikawada… - Biochemistry, 2010 - ACS Publications
Anhydrobiotic (ie, life without water) organisms are known to produce group 3 late embryogenesis
abundant (G3LEA) proteins during adaptation to severely water-deficient conditions. …

The induction of anhydrobiosis in the sleeping chironomid: current status of our knowledge

R Cornette, T Kikawada - IUBMB life, 2011 - Wiley Online Library
An African chironomid, Polypedilum vanderplanki, is the only insect known to be capable of
extreme desiccation tolerance, or anhydrobiosis. In the 1950s and 1960s, Hinton …

The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral …

…, S Kikuta, M Watanabe, R Cornette, T Kikawada… - Insect biochemistry and …, 2010 - Elsevier
We recently cloned a trehalose transporter gene (Tret1) that contributes to anhydrobiosis
induction in the sleeping chironomid Polypedilum vanderplanki Hinton. Because trehalose is …

Increase of internal ion concentration triggers trehalose synthesis associated with cryptobiosis in larvae of Polypedilum vanderplanki

M Watanabe, T Kikawada… - Journal of Experimental …, 2003 - journals.biologists.com
Larvae of an African chironomid, Polypedilum vanderplanki, which live in temporal rock
pools, are completely dehydrated when the pools dry up and undergo anhydrobiosis until the …

[HTML][HTML] Anhydrobiosis-associated nuclear DNA damage and repair in the sleeping chironomid: linkage with radioresistance

…, R Cornette, T Sakashita, N Hamada, T Kikawada… - PloS one, 2010 - journals.plos.org
Anhydrobiotic chironomid larvae can withstand prolonged complete desiccation as well as
other external stresses including ionizing radiation. To understand the cross-tolerance …