A fundamental property of animal cells is the ability to regulate their own cell volume. Even
under hypotonic stress imposed by either decreased extracellular or increased intracellular …

Apoptotic volume decrease is a pivotal event triggering a cell to undergo apoptosis and is
induced by ionic effluxes resulting mainly from increased K + and Cl - conductances. Here, we …

Stretch- and swelling-activated cation (SSAC) channels play essential roles not only in sensing
and transducing external mechanical stresses but also in regulating cell volume in living …

This work studied the design, fabrication, and performance evaluation of a 36cm 2 , passive,
air-breathing, room-temperature, direct methanol fuel cell (DMFC). The cell is completely …

TMEM16 (transmembrane protein 16) proteins, which possess eight putative transmembrane
domains with intracellular NH 2 - and COOH-terminal tails, are thought to comprise a Cl − …

Recent innovations in the next-generation sequencing technologies have unveiled that the
accumulation of genetic alterations results in the transformation of normal cells into cancer …

Mutations in the human ATP13A2 (PARK9), a lysosomal ATPase, cause Kufor-Rakeb Syndrome,
an early-onset form of Parkinson’s disease (PD). Here, we demonstrate that ATP13A2 …

Background & Aims Helicobacter pylori infection is a risk factor for gastric cancer. To
explore the genetic basis of gastric cancer that develops in inflamed gastric mucosa, we …

10.7554/eLife.28080.001 Myelin, made by oligodendrocytes, is essential for rapid
information transfer in the central nervous system. Oligodendrocyte precursors (OPs) receive …

It has recently been shown that shear stress augments the heterologously expressed TRPM7
channel activity by exocytosis-mediated incorporation of TRPM7 into the plasma membrane…