User profiles for Takeshi Kurita

Takeshi Kurita

Tokyo Medical and Dental University
Verified email at tmd.ac.jp
Cited by 7445

Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer

JJ Kim, T Kurita, SE Bulun - Endocrine reviews, 2013 - academic.oup.com
Progesterone receptor (PR) mediates the actions of the ovarian steroid progesterone, which
together with estradiol regulates gonadotropin secretion, prepares the endometrium for …

Progesterone is essential for maintenance and growth of uterine leiomyoma

…, K Ishi, VA Serna, R Kakazu, SE Bulun, T Kurita - …, 2010 - academic.oup.com
Uterine leiomyomata (ULs) represent the most common tumor in women and can cause
abnormal uterine bleeding, large pelvic masses, and recurrent pregnancy loss. Although the …

Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development

…, SW Hayward, YZ Wang, AA Donjacour, T Kurita - The Journal of steroid …, 2004 - Elsevier
This review on normal and neoplastic growth of the prostate emphasizes the importance of
epithelial–mesenchymal/stromal interactions. Accordingly, during prostatic development …

Role of stromal-epithelial interactions in hormonal responses

GR Cunha, PS Cooke, T Kurita - Archives of histology and cytology, 2004 - jstage.jst.go.jp
Steroid sex hormones (17β-estradiol, testosterone, dihydrotestosterone, and progesterone)
and aryl hydrocarbons such as the dioxins regulate epithelial proliferation and secretory …

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

…, K Smalley, C Magraw, VA Serna, T Kurita… - …, 2012 - journals.biologists.com
The transcription factor p63 is important in the development of the skin as p63-null mice exhibit
striking defects in embryonic epidermal morphogenesis. Understanding the mechanisms …

Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogen-induced uterine epithelial cell deoxyribonucleic acid synthesis

T Kurita, P Young, JR Brody, JP Lydon… - …, 1998 - academic.oup.com
The role of epithelial and stromal progesterone (P) receptors (PR) in the regulation of
uterine epithelial DNA synthesis by P was investigated by analyzing the four types of tissue …

Role of p63 and basal cells in the prostate

T Kurita, RT Medina, AA Mills, GR Cunha - 2004 - journals.biologists.com
The prostate contains two major epithelial cell types – luminal and basal cells - both of which
develop from urogenital sinus epithelium. The cell linage relationship between these two …

Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth

…, D Chakravarti, JJ Kim, T Kurita… - Proceedings of the …, 2013 - National Acad Sciences
Uterine leiomyomas are extremely common estrogen and progesterone-dependent tumors
of the myometrium and cause irregular uterine bleeding, severe anemia, and recurrent …

Epithelial–stromal tissue interaction in paramesonephric (Müllerian) epithelial differentiation

T Kurita, PS Cooke, GR Cunha - Developmental biology, 2001 - Elsevier
During organogenesis, the middle to caudal portion of Müllerian epithelium differentiates
into uterine and vaginal epithelia in females. Functional differentiation of uterine and vaginal …

Role of stromal and epithelial estrogen receptors in vaginal epithelial proliferation, stratification, and cornification

DL Buchanan, T Kurita, JA Taylor, DB Lubahn… - …, 1998 - academic.oup.com
Estradiol 17-β (E 2 ) induces epithelial proliferation, stratification, and cornification in vaginal
epithelium. Our aim was to determine the respective roles of epithelial and stromal estrogen …