The mechanistic target of rapamycin (mTOR) kinase forms two multi-protein signaling
complexes, mTORC1 and mTORC2, which are master regulators of cell growth, metabolism, …

G-protein signaling depends on the ability of the individual subunits of the G-protein
heterotrimer to assemble into a functional complex. Formation of the G-protein βγ (Gβγ) dimer is …

Objectives The objectives of this study were to investigate the pathophysiology of Kawasaki
disease (KD) from immunological and oxidative stress perspectives, and to identify real‐time …

Bardet-Biedl syndrome (BBS) is a genetic disorder characterized by malfunctions in primary
cilia resulting from mutations that disrupt the function of the BBSome, an 8-subunit complex …

Bardet-Biedl syndrome (BBS) is a rare genetic disease that causes retinal degradation,
obesity, kidney dysfunction, polydactyly, and other cilium-related disorders. To date, more than …

The mTOR signalling complex 1 (mTORC 1) is a master regulator of cell growth and a high‐value
drug target. While mTORC1 function has been studied extensively, little is known …

Bardet‐Biedl syndrome (BBS) stems from failed assembly of BBS proteins into a functional
protein complex called the BBSome. The BBSome consists of eight BBS proteins (1–2, 4–5, 7…

The mechanistic target of rapamycin (mTOR) kinase forms two multi‐protein signaling
complexes, mTORC1 and mTORC2, which are master regulators of cell growth, metabolism, …

We systematically investigated, for the first time, the relationship between regioselectivity
and acid/base effects in the cyclization reactions between carboxylic acids and carbon−carbon …

… He assisted a graduate student, Takuma Aoba, in this work. They used a combination of …
He also worked with Takuma Aoba to determine the role of the chaperonin CCT and its co-…