To the Editor—The cloning and subsequent engineering of fluorescent proteins (FPs) has
revolutionized methods in biological research1, 2. There are now thousands of FPs available, …

Activity‐dependent changes in gene‐expression are believed to underlie the molecular
representation of memory. In this study, we report that in vivo activation of neurons rapidly …

Environmental enrichment paradigms that incorporate cognitive stimulation, exercise, and
motor learning benefit memory and synaptic plasticity across the rodent lifespan. However, the …

The contrast and resolution of images obtained with optical microscopes can be improved
by deconvolution and computational fusion of multiple views of the same sample, but these …

Lipid droplets (LDs) originate from the endoplasmic reticulum (ER) to store triacylglycerol (TG)
and cholesterol esters. The ER protein seipin was shown to localize to ER-LD contacts …

Structured illumination microscopy (SIM) doubles the spatial resolution of a fluorescence
microscope without requiring high laser powers or specialized fluorophores. However, the …

Overexpression of the amyloid precursor protein (APP) in hippocampal neurons leads to
elevated β-amyloid peptide (Aβ) production and consequent depression of excitatory …

It is known that interactions between nociceptors and dendritic cells (DCs) can modulate
immune responses in barrier tissues. However, our understanding of the underlying …

Although environmental enrichment has been shown to improve various types of memory in
young and aging mice, no study has directly compared the degree to which enrichment …

In 2014, the Nobel Prize in Chemistry was awarded to three scientists who have made
groundbreaking contributions to the field of superresolution (SR) microscopy (SRM). The first …