User profiles for Tamás A. Martinek

Tamás Martinek

University of Szeged
Verified email at med.u-szeged.hu
Cited by 4919

Peptidic foldamers: ramping up diversity

TA Martinek, F Fülöp - Chemical Society Reviews, 2012 - pubs.rsc.org
Non-natural folded polymers (foldamers) display considerable versatility, and the design of
such molecules is of great current interest. In this respect, peptidic foldamers are perhaps the …

Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides

…, G Olajos, O Méhi, B Bálint, I Nagy, TA Martinek… - Nature …, 2018 - nature.com
Antimicrobial peptides are promising alternative antimicrobial agents. However, little is
known about whether resistance to small-molecule antibiotics leads to cross-resistance (…

Peptides containing β-amino acid patterns: challenges and successes in medicinal chemistry

C Cabrele, TA Martinek, O Reiser… - Journal of Medicinal …, 2014 - ACS Publications
The construction of bioactive peptides using β-amino acid-containing sequence patterns is
a very promising strategy to obtain analogues that exhibit properties of high interest for …

Application of alicyclic β-amino acids in peptide chemistry

F Fülöp, TA Martinek, GK Tóth - Chemical Society Reviews, 2006 - pubs.rsc.org
The self-organizing β-peptides have attracted considerable interest in the fields of foldamer
chemistry and biochemistry. These compounds exhibit various stable secondary structure …

Performance of the general amber force field in modeling aqueous POPC membrane bilayers

B Jójárt, TA Martinek - Journal of computational chemistry, 2007 - Wiley Online Library
The aim of this work was to answer the question of whether the general amber force field (GAFF)
is good enough to simulate fully hydrated POPC membrane bilayers. The test system …

[PDF][PDF] Design of peptidic foldamer helices: a stereochemical patterning approach

IM Mándity, E Wéber, TA Martinek… - Angewandte …, 2009 - publicatio.bibl.u-szeged.hu
Folded polymers are utilized in virtually all vital processes in nature. Non-natural folded
polymers (foldamers) have the potential for being similarly or even more versatile, and the …

Effects of the alternating backbone configuration on the secondary structure and self-assembly of β-peptides

TA Martinek, IM Mándity, L Fülöp, GK Tóth… - Journal of the …, 2006 - ACS Publications
Heterochiral homo-oligomers with alternating backbone configurations were constructed by
using the different enantiomers of the cis- and trans-2-aminocyclopentanecarboxylic acid (…

Chain-length-dependent helical motifs and self-association of β-peptides with constrained side chains

A Hetényi, IM Mándity, TA Martinek… - Journal of the …, 2005 - ACS Publications
Homo-oligomers constructed by using trans-2-aminocyclohexanecarboxylic acid monomers
without protecting groups were studied. Both ab initio theory and NMR measurements …

Unique α,β‐ and α,α,β,β‐Peptide Foldamers Based on cis‐β‐Aminocyclopentanecarboxylic Acid

…, E Wéber, IM Mándity, C Cabrele, TA Martinek… - Angewandte Chemie …, 2012 - infona.pl
Unique α,β‐ and α,α,β,β‐Peptide Foldamers Based on cis‐β‐Aminocyclopentanecarboxylic
Acid × Close The Infona portal uses cookies, ie strings of text saved by a browser on the user's …

Building β-peptide H10/12 foldamer helices with six-membered cyclic side-chains: Fine-tuning of folding and self-assembly

…, L Fülöp, E Vass, GK Tóth, TA Martinek… - Organic …, 2010 - ACS Publications
The ability of the β-peptidic H10/12 helix to tolerate side-chains containing six-membered
alicyclic rings was studied. cis-2-Aminocyclohex-3-ene carboxylic acid (cis-ACHEC) residues …