Consistent failure over the past few decades to reduce the high prevalence of stress-related
disorders has motivated a search for alternative research strategies. Resilience refers to the …

Exposure to traumatic events that produce extreme fear and horror is all too common in both
military and civilian populations, but not all individuals develop posttraumatic stress …

Background: A central problem in posttraumatic stress disorder (PTSD) is a reduced
capacity to suppress fear under safe conditions. Previously, we have shown that combat‐related …

The study of inflammation in fear-and anxiety-based disorders has gained interest as growing
literature indicates that pro-inflammatory markers can directly modulate affective behavior. …

Annually, approximately 30 million patients are discharged from the emergency department
(ED) after a traumatic event 1 . These patients are at substantial psychiatric risk, with …

Pituitary adenylate cyclase-activating polypeptide (PACAP) is known to broadly regulate the
cellular stress response. In contrast, it is unclear if the PACAP–PAC1 receptor pathway has …

A dysregulated fear response is one of the hallmark clinical presentations of patients suffering
from posttraumatic stress disorder (PTSD). These patients show over-generalization of …

Objective The authors examined the effectiveness of virtual reality exposure augmented
with d-cycloserine or alprazolam, compared with placebo, in reducing posttraumatic stress …

BACKGROUND:: The symptoms of posttraumatic stress disorder (PTSD) can be explained, at
least in part, as an inability to inhibit learned fear during conditions of safety. Our group has …

Background Many studies report smaller hippocampal and amygdala volumes in posttraumatic
stress disorder (PTSD), but findings have not always been consistent. Here, we present …