User profiles for Tapan Kumar Mistri
 | Dr. Tapan Kumar MistriPhD from National University of Singapore Verified email at srmist.edu.in Cited by 389 |
Transcription factors in SOX family: Potent regulators for cancer initiation and development in the human body
P Kumar, TK Mistri - Seminars in cancer biology, 2020 - Elsevier
Transcription factors (TFs) have a key role in controlling the gene regulatory network that
sustains explicit cell states in humans. However, an uncontrolled regulation of these genes …
sustains explicit cell states in humans. However, an uncontrolled regulation of these genes …
Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells
TK Mistri, AG Devasia, LT Chu, WP Ng, F Halbritter… - EMBO …, 2015 - embopress.org
Embryonic stem cell ( ESC ) identity is orchestrated by co‐operativity between the transcription
factors ( TF s) Sox2 and the class V POU ‐ TF Oct4 at composite Sox/Oct motifs. Neural …
factors ( TF s) Sox2 and the class V POU ‐ TF Oct4 at composite Sox/Oct motifs. Neural …
DNA-dependent Oct4–Sox2 interaction and diffusion properties characteristic of the pluripotent cell state revealed by fluorescence spectroscopy
CS Lam, TK Mistri, YH Foo, T Sudhaharan… - Biochemical …, 2012 - portlandpress.com
Oct4 and Sox2 are two essential transcription factors that co-regulate target genes for the
maintenance of pluripotency. However, it is unclear whether they interact prior to DNA binding …
maintenance of pluripotency. However, it is unclear whether they interact prior to DNA binding …
Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through Fgf4/Fgfr2 signaling in preimplantation mouse embryos
TK Mistri, W Arindrarto, WP Ng, C Wang… - Biochemical …, 2018 - portlandpress.com
Oct4 and Sox2 regulate the expression of target genes such as Nanog, Fgf4, and Utf1, by
binding to their respective regulatory motifs. Their functional cooperation is reflected in their …
binding to their respective regulatory motifs. Their functional cooperation is reflected in their …
Co-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cells
Transcription factors (TF) often bind in heterodimeric complexes with each TF recognizing a
specific neighboring cis element in the regulatory region of the genome. Comprehension of …
specific neighboring cis element in the regulatory region of the genome. Comprehension of …
Investigation of bio-active Amaryllidaceae alkaloidal small molecules as putative SARS-CoV-2 main protease and host TMPRSS2 inhibitors: interpretation by in-silico …
The novel coronavirus disease 2019 (Covid-19) outburst is still threatening global health.
This highly contagious viral disease is caused by the infection of SARS-CoV-2 virus. Covid-19 …
This highly contagious viral disease is caused by the infection of SARS-CoV-2 virus. Covid-19 …
Fluorene-induced stress in the benthic oligochaete Tubifex tubifex: A multi-biomarker assessment of toxicological pathways and mechanisms under acute and …
This study examined the multifaceted impacts of fluorene exposure on Tubifex tubifex,
encompassing acute (survival analysis and behavioral responses) and subchronic exposure …
encompassing acute (survival analysis and behavioral responses) and subchronic exposure …
How effective is direct targeting of genes instead of gene products in providing promising lead: Lessons from discovery of naphthyridine-azaquinilone as lead for …
TK Mistri, S Porwal - AIP Conference Proceedings, 2024 - pubs.aip.org
Recent advancements in next-generation sequencing (NSG) have deciphered many genes
and genetic abnormalities associated with human diseases. It would be a promising strategy …
and genetic abnormalities associated with human diseases. It would be a promising strategy …
Identification of potential 3CLpro inhibitors-modulators for human norovirus infections: An advanced virtual screening approach
The present study aimed to screen small molecular compounds as the human noroviruses (HuNoV)
inhibitors/modulators that could be potentially responsible for exhibiting some level …
inhibitors/modulators that could be potentially responsible for exhibiting some level …
[PDF][PDF] Quantitative determination of Oct4-Sox2 heterodimer formation with nanog promoter element
TK Mistri, CS Lam, W Arindrarto, D Rodda, YH Foo… - Biophysical …, 2011 - cell.com
Oct4 and Sox2 are key transcription factors (TFs) essential for maintaining pluripotency as
well as the self-renewal ability of embryonic stem cells (ESC). Oct4 and Sox2 have been …
well as the self-renewal ability of embryonic stem cells (ESC). Oct4 and Sox2 have been …