Rituximab (RTX), an antibody targeting CD20, is widely used as a first-line therapeutic strategy
in B cell–mediated autoimmune diseases. However, a large proportion of patients either …

Previous data have suggested that B-cell–depletion therapy may induce the settlement of
autoreactive long-lived plasma cells (LLPCs) in the spleen of patients with autoimmune …

Objective This study was undertaken to characterize kidney and urine antibody‐secreting
cells (ASCs) from patients with active lupus nephritis, before and after induction therapy. …

Marginal zone (MZ) B cells are one of the main actors of T-independent (TI) responses in
mice. To identify the B cell subset(s) involved in such responses in humans, we vaccinated …

Immune thrombocytopenia (ITP) is an autoimmune disease mediated by pathogenic
antibodies directed against platelet antigens, including GPIIbIIIa. Taking advantage of spleen …

Klhl6 belongs to the KLHL gene family, which is composed of an N-terminal BTB-POZ domain
and four to six Kelch motifs in tandem. Several of these proteins function as adaptors of …

Background: Pathogenic antibody secreting cells (ASC) have been identified in the kidney
of SLE-prone mice, but are poorly characterized in human lupus nephritis (LN). We …

Neurophysiological studies suggest that abnormal neural inhibition may explain a range of
sensory processing differences in autism spectrum disorders (ASD). In particular, the …

Background/Purpose Pathogenic antibody-secreting cells (ASC) are poorly characterized in
human lupus nephritis (LN). Our objective was to compare the single cell molecular …

In this paper, we describe a production procedure of the one-to-one double helical complex
of poly(dG)–poly(dC), characterized by a well-defined length (up to 10 kb) and narrow size …