We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies
have identified common CKD susceptibility variants. The CKDGen consortium performed …

Through genome-wide association meta-analyses of up to 133,010 individuals of European
ancestry without diabetes, including individuals newly genotyped using the Metabochip, we …

Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory
arthritis. By combining data from >140,000 individuals of European ancestry within the Global …

There is evidence across several species for genetic control of phenotypic variation of
complex traits 1 , 2 , 3 , 4 , such that the variance among phenotypes is genotype dependent. …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22
genome-wide association studies (GWAS) in 38,968 women of European descent, with …

Thyroid hormones are necessary for the normal functioning of physiological systems.
Therefore, knowledge of any factor (whether genetic, environmental or intrinsic) that alters the …

Chronic kidney disease (CKD) is an important public health problem with a genetic component.
We performed genome-wide association studies in up to 130,600 European ancestry …

Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial
genetic contribution. Genetic variation influencing blood pressure has the potential to …