Robotic search for optimal cell culture in regenerative medicine

…, T Masuda, M Nishida, CT Watanabe, T Higashi… - Elife, 2022 - elifesciences.org
Induced differentiation is one of the most experience-and skill-dependent experimental
processes in regenerative medicine, and establishing optimal conditions often takes years. We …

Complementation characteristics of newly isolated mutants from two groups of strains of Clostridium perfringens.

T Imagawa, T Tatsuki, Y Higashi, T Amano - Biken Journal, 1981 - europepmc.org
1. Mutants of a group were converted to b group by a second NG treatment. The resulting b
group mutants could not produce the marker products that had been lost on the first NG …

Human CYP2A6 is induced by estrogen via estrogen receptor

E Higashi, T Fukami, M Itoh, S Kyo, M Inoue… - Drug Metabolism and …, 2007 - ASPET
Human CYP2A6, which is predominantly expressed in liver, is a key enzyme responsible for
the metabolism of nicotine, coumarin, and some pharmaceutical drugs. CYP2A6 is also …

Human CYP2A6 is regulated by nuclear factor-erythroid 2 related factor 2

S Yokota, E Higashi, T Fukami, T Yokoi… - Biochemical …, 2011 - Elsevier
Human CYP2A6 is responsible for the metabolism of nicotine and coumarin as well as the
metabolic activation of tobacco-related nitrosamines. Earlier studies revealed that CYP2A6 …

An activity which restores theta toxin activity in some theta toxin-deficient mutants of Clostridium perfringens

T Imagawa, Y Higashi - Microbiology and immunology, 1992 - jstage.jst.go.jp
Higashi et al (2) reported that a clear hemolytic zone was formed around mixed colonies
when a certain combination of theta toxin-deficient mutants of C. perfringens type A strain was …

[PDF][PDF] ISOLATED MUTANTS FROM T\\70 GROUPS OF STRAINS OF CLOSTRIDIUM PI, RFR/A1GENS

T IMACAWA, TRUTYAH HiGASH - BIKEN JOURNAL, 1981 - ir.library.osaka-u.ac.jp
… fronl tt group mutants (Higashi at a1. , 1973 ; Higashi at a1. , 1976). Further studies on this
phenomenon revealed that respective negative mutants of I-toxin (rennet-like proteasc), "- …

Rheological Properties of Dioscorea alata L.(Daijo) and Dioscorea japonicaTHUNB.(Jinenjo)

K TATSUKI - Journal of Home Economics of Japan, 1993 - jstage.jst.go.jp
大薯および自然薯のレオロジー的性質を一層明らかにするため, 生の粘弾性, テスクチャー (これら
から調製した饅頭の皮も含む), 線切り, 短冊切りの破断特性, 前報以外の切片組織の顕鏡およびすり…

Regulation of toxin production in Clostridium perfringens

T Shimizu, A Okabe, JI Rood - The Clostridia, 1997 - Elsevier
Publisher Summary This chapter focuses on regulation of toxin production in Clostridium
Perfringens. The most significant of these toxins are the α-toxin, θ-toxin, and κ-toxin. The genes …

[PDF][PDF] Further Studies on Complementation Between Mutants of Clostridium perfringens.

T Tatsuki, T Imagawa, H Kitajima, Y Higashi… - Biken …, 1981 - ir.library.osaka-u.ac.jp
4. The activities of 12 extracellular enzymes, including sialidase, of several b group strains
and the parent PB6K were compared, but no definite differences were observed. From this …

FDG accumulation in schwannomas: Pathological and morphological characteristics

K Miyake, Y Nakamoto, T Kataoka, T Higashi… - 2013 - Soc Nuclear Med
233 Objectives Schawannoma is known as a benign tumor which occasionally shows high F-18
fluorodeoxyglucose (FDG) uptake. We investigated the pathological and morphological …