Increased intraocular pressure (IOP) represents a major risk factor for glaucoma, a prevalent
eye disease characterized by death of retinal ganglion cells; lowering IOP is the only …

Most irreversible blindness results from retinal disease. To advance our understanding of
the etiology of blinding diseases, we used single-cell RNA-sequencing (scRNA-seq) to …

The anterior segment of the eye consists of the cornea, iris, ciliary body, crystalline lens, and
aqueous humor outflow pathways. Together, these tissues are essential for the proper …

… (E) Transcriptional relationship of the astrocyte types identified in this study to retinal astrocytes
profiled in van Zyl et al. (9). The color and size of each dot reflect the percentage of cells …

High-acuity vision in primates, including humans, is mediated by a small central retinal region
called the fovea. As more accessible organisms lack a fovea, its specialized function and …

Purpose To identify barriers to follow-up eye care in children who failed a visual acuity
screening conducted by their primary care provider. Methods Children aged 3-14 years who …

… Tavé van Zyl, MD, is an ophthalmology resident at Massachusetts Eye and Ear Infirmary in
Boston, MA. Born in South Africa and raised in Canada, she studied biochemical sciences at …

Primary open-angle glaucoma (POAG), characterized by retinal ganglion cell death, is a
leading cause of irreversible blindness worldwide. However, its molecular and cellular causes …

Glaucoma is a leading cause of blindness. Current glaucoma medications work by lowering
intraocular pressure (IOP), a risk factor for glaucoma, but most treatments do not directly …

Purpose To describe the characteristics and outcomes of endogenous endophthalmitis.
Design Retrospective case series. Participants Patients with endogenous endophthalmitis. …