Epigenetic defects caused by hereditary or de novo mutations are implicated in various
human diseases. It remains uncertain whether correcting the underlying mutation can reverse …

Myotonic dystrophy type 1 (DM1) results from a CTG repeat expansion in the 3’-UTR of
DMPK. When the repeat extensively expands, this results in DMPK aberrant methylation, …

Epimutations refer to mistakes in the setting or maintenance of epigenetic marks in the chromatin.
They lead to mis-expression of genes and are often secondary to germline transmitted …

Myotonic dystrophy type 1 (DM1) is a highly variable, multisystem condition that develops as
a result of an unstable trinucleotide repeat CTG expansion at the 3′-untranslated region of …

Epimutations are the cause of a considerable number of genetically inherited conditions in
humans. All result from the mis-expression of genes due to epigenetic changes that are …

… Tayma Handal and Rachel Eiges from The Hebrew University School of Medicine focus
on the contribution of human iPSCs to the study of myotonic dystrophy type 1. Ponlapat …

The acquisition of cell fate is dependent on gene regulatory networks that are regulated
spatiotemporally by cell type specific transcription factors (TFs). In binding to a class of cis-…

… impor bahan makanan, karena itu kehidupan ekonominya yang khas adalah di bidang
perniagaan dan kemungkinan besar hanya bersifat moneter, karena masyarakatnya handal …

… To my two little sons Mohammad and Tayma’, I wish you would always look up to me. … Nader
Handal at Caritas Baby Hospital. The pedigrees were constructed through family interviews. …

… Tugas utama Badan Kepegawaian Daerah sebagai perangkat daerah adalah mewujudkan
manajemen kepegawaian daerah yang handal, untuk menciptakan aparatur PNS yang …