Angioinvasion is a hallmark of mucormycosis. Previously, we identified endothelial cell
glucose-regulated protein 78 (GRP78) as a receptor for Mucorales that mediates host cell …

Rhizopus oryzae is the most common cause of mucormycosis, an angioinvasive fungal
infection that causes more then 50% mortality rate despite first‐line therapy. Clinical and animal …

We previously found that caspofungin synergized with amphotericin B lipid complex in
treating murine mucormycosis. We now report a similarly enhanced activity of liposomal …

Mucormycosis is a life-threatening infection caused by Mucorales fungi. Here we sequence
30 fungal genomes, and perform transcriptomics with three representative Rhizopus and …

Patients with diabetic ketoacidosis (DKA) are uniquely predisposed to mucormycosis, an
angioinvasive fungal infection with high mortality. Previously, we demonstrated that Rhizopus …

Mucormycosis is an aggressive, life-threatening infection caused by fungi in the order
Mucorales. The current diagnosis of mucormycosis relies on mycological cultures, radiology and …

Mucormycosis, caused by Rhizopus species, is a life-threatening fungal infection that occurs
in patients immunocompromised by diabetic ketoacidosis (DKA), cytotoxic chemotherapy, …

We compared the efficacy of combination posaconazole-liposomal amphotericin B (LAmB)
therapy to monotherapy with either drug in diabetic ketoacidotic or neutropenic mice with …

Decades of previous efforts to develop renal-sparing polyene antifungals were misguided
by the classic membrane permeabilization model 1 . Recently, the clinically vital but also …

We have previously reported that vaccination with rAls3p-N protein of Candida albicans,
formulated with alum adjuvant (also designated as NDV-3) protects immunocompetent mice …