User profiles for Teresa Nutile
Teresa NutileTecnologo, Istituto Genetica e Biofisica, CNR, Napoli Verified email at igb.cnr.it Cited by 10114 |
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
…, PJ Munson, P Nandakumar, QT Nguyen, T Nutile… - Nature …, 2017 - nature.com
Elevated blood pressure is the leading heritable risk factor for cardiovascular disease
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) …
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) …
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
…, SE Medland, IM Nolte, R Noordam, T Nutile… - Nature …, 2017 - nature.com
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated
with various adult diseases. Using 1000 Genomes Project–imputed genotype data in up to …
with various adult diseases. Using 1000 Genomes Project–imputed genotype data in up to …
Meta-analysis of genome-wide association studies for personality
Personality can be thought of as a set of characteristics that influence people's thoughts,
feelings and behavior across a variety of settings. Variation in personality is predictive of many …
feelings and behavior across a variety of settings. Variation in personality is predictive of many …
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
Menopause timing has a substantial impact on infertility and risk of disease, including breast
cancer, but the underlying mechanisms are poorly understood. We report a dual strategy in …
cancer, but the underlying mechanisms are poorly understood. We report a dual strategy in …
Seventy-five genetic loci influencing the human red blood cell
…, MF Moffatt, M Nauck, M Novatchkova, T Nutile… - Nature, 2012 - nature.com
Anaemia is a chief determinant of global ill health, contributing to cognitive impairment,
growth retardation and impaired physical capacity. To understand further the genetic factors …
growth retardation and impaired physical capacity. To understand further the genetic factors …
[PDF][PDF] Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is
associated with multiple complex diseases. The genetic determinants of chronic inflammation …
associated with multiple complex diseases. The genetic determinants of chronic inflammation …
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
…, T Nabika, E Nakashima, HK Ng, K Nikus, T Nutile… - Nature …, 2015 - nature.com
We carried out a trans-ancestry genome-wide association and replication study of blood
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder
Importance Neuroticism is a pervasive risk factor for psychiatric conditions. It genetically
overlaps with major depressive disorder (MDD) and is therefore an important phenotype for …
overlaps with major depressive disorder (MDD) and is therefore an important phenotype for …
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
The genetic architecture of human reproductive behavior—age at first birth (AFB) and number
of children ever born (NEB)—has a strong relationship with fitness, human development, …
of children ever born (NEB)—has a strong relationship with fitness, human development, …