New methods for the quantification of ingested nano-and ultrafine plastics in seabirds

…, T Rodemann, KA Mylius, TL Pinfold… - Environmental …, 2022 - ACS Publications
Plastic ingestion has been documented in a plethora of taxa. However, there is a significant
gap in the detection of nano- and ultrafine particles due to size limitations of commonly used …

A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers

…, PR Lennard, PR Murphy, CEB Ong, TL Pinfold… - Science …, 2020 - science.org
Around 40% of humans and Tasmanian devils (Sarcophilus harrisii) develop cancer in their
lifetime, compared to less than 10% for most species. In addition, devils are affected by two …

[HTML][HTML] Novel methods to manipulate autolysis in sparkling wine: effects on yeast

…, SA Schmidt, DC Close, K Goemann, TL Pinfold… - Molecules, 2021 - mdpi.com
Sparkling wine made by the traditional method (Méthode Traditionelle) develops a distinct
and desirable flavour and aroma profile attributed to proteolytic processes during prolonged …

[HTML][HTML] Mouse model of devil facial tumour disease establishes that an effective immune response can be generated against the cancer cells

TL Pinfold, GK Brown, SS Bettiol… - Frontiers in …, 2014 - frontiersin.org
The largest carnivorous marsupial in Australia, the Tasmanian devil (Sarcophilus harrisii) is
facing extinction in the wild due to a transmissible cancer known as Devil Facial Tumour …

Tasmanian devil CD28 and CTLA4 capture CD80 and CD86 from adjacent cells

C Wong, JM Darby, PR Murphy, TL Pinfold… - Developmental & …, 2021 - Elsevier
Immune checkpoint immunotherapy is a pillar of human oncology treatment with potential
for non-human species. The first checkpoint immunotherapy approved for human cancers …

Generation and testing of fluorescent adaptable simple theranostic (FAST) proteins

AS Flies, JM Darby, PR Murphy, TL Pinfold… - Bio …, 2020 - bio-protocol.org
This protocol provides a step-by-step method to create recombinant fluorescent fusion proteins
that can be secreted from mammalian cell lines. This builds on many other recombinant …

[HTML][HTML] Seasonality of phytoplankton growth limitation by iron and manganese in subantarctic waters

…, PW Boyd, MJ Ellwood, TL Pinfold… - Elementa: Science of …, 2023 - online.ucpress.edu
Phytoplankton indirectly influence climate through their role in the ocean biological carbon
pump. In the Southern Ocean, the subantarctic zone represents an important carbon sink, yet …

Seasonality of phytoplankton growth limitation by iron and manganese in subantarctic waters

…, LT Bach, PW Boyd, MJ Ellwood, TL Pinfold… - Authorea …, 2022 - essopenarchive.org
Phytoplankton indirectly influence the climate, through their role in the ocean biological
carbon pump. Hence factors limiting phytoplankton growth directly impact the strength of the …

Immune checkpoint proteins are conserved across 160 million years of evolution and are expressed on transmissible cancers

…, PR Lennard, PR Murphy, CEB Ong, TL Pinfold… - bioRxiv, 2019 - biorxiv.org
Around 40% of humans and captive Tasmanian devils (Sarcophilus harrisii) develop cancer,
compared to less than 10% for most species. Tasmanian devils also suffer from two of the …

Abstract B040: Imiquimod initiates tumor specific overload of the ER stress response in Tasmanian devil facial cancer cells

AL Patchett, TL Pinfold, C Tovar, B Lyons… - Cancer Immunology …, 2016 - AACR
Background: The potent immune modifier imiquimod (R-837) induces apoptosis of various
tumor cell lines by mechanisms that are not fully understood. As a topical immunotherapy, …