Ligands of the TGF-β superfamily (including the TGF-βs, Nodal and BMPs) play instructive
roles during embryonic development. This is achieved by regulation of genes important for …

The interplay between sequence-specific DNA-binding transcription factors, histone-modifying
enzymes, and chromatin-remodeling enzymes underpins transcriptional regulation. …

10.7554/eLife.21666.001 Repetitive sequences derived from transposons make up a large
fraction of eukaryotic genomes and must be silenced to protect genome integrity. Repetitive …

10.7554/eLife.22474.001 NODAL/Activin signaling orchestrates key processes during embryonic
development via SMAD2. How SMAD2 activates programs of gene expression that are …

SMAD2, an effector of the NODAL/Activin signalling pathway, regulates developmental
processes by sensing distinct chromatin states and interacting with different transcriptional …

McMurchy AN, Stempor P, Gaarenstroom T, Wysolmerski B, Dong Y, Aussianikava D, Appert
A, Huang N, Kolasinska-Zwierz P, Sapetschnig A, Miska EA, Ahringer J. 2017. A team of …

Ligands of the TGF-β/Activin/Nodal family signal through SMAD2/3 transcription factors, which
recognize a very short DNA consensus sequence. Their genomic target sites therefore are …

… We thank Wei Qiang Seow, Tessa Gaarenstroom and Andrea Frapporti for their thoughtful
comments on the manuscript. JS was supported by a Medical Research Council DTP …

Climate warming in the Arctic has led to warmer and earlier springs, and as a result, many
food resources for migratory animals become available earlier in the season, as well as …

… We thank Tessa Gaarenstroom for critical reading of the article. FNC was supported by an
SNF postdoctoral fellowship (P2LAP3_171808), GS by a Newton International Fellowship (…