Living bacteria therapies have been proposed as an alternative approach to treating a
broad array of cancers. In this study, we developed a genetically encoded microbial …

Engineered bacteria for therapeutic applications would benefit from control mechanisms
that confine the growth of the bacteria within specific tissues or regions in the body. Here we …

Background Zinc is an essential micronutrient with diverse biological roles in cell growth,
apoptosis and metabolism, and in the regulation of endocrine, immune, and neuronal functions …

The prevalence of tumor-colonizing bacteria along with advances in synthetic biology are
leading to a new generation of living microbial cancer therapies. Because many bacterial …

Bacteria are emerging as living drugs to treat a broad range of disease indications. However,
the inherent advantages of these replicating and immunostimulatory therapies also carry …

Synthetic biology is transforming therapeutic paradigms by engineering living cells and
microbes to intelligently sense and respond to diseases including inflammation, infections, …

Objective To determine predictors of time to readmission to a general psychiatry inpatient
unit. Method Data from the Minimum Data Set-Mental Health (MDS-MH), a standardized …

Respiratory syncytial virus (RSV) infection occurs commonly in infants aged ≤2 years, and
severe infection results in hospitalization with accompanying morbidity and mortality. …

Background: Respiratory syncytial virus (RSV) infection frequently results in RSV-related
hospitalization (RSVH) in young infants. We examined the outcomes of palivizumab recipients …

Objective: To determine risk factors for clinically significant progression during 12 months in
patients with mild-to-moderate Alzheimer disease. Method: Community-dwelling patients …