Background Current methods used for annotating metagenomics shotgun sequencing (MGS)
data rely on a computationally intensive and low-stringency approach of mapping each …

Prostate cancer (PCa) is frequently diagnosed in men, and dysregulation of microRNAs is
characteristic of many cancers. MicroRNA-1207-3p is encoded at the non-protein coding gene …

Bacterial natural products have inspired the development of numerous antibiotics in use
today. As resistance to existing antibiotics has become more prevalent, new antibiotic lead …

Tuberculosis (TB) remains one of the deadliest infectious diseases. Unfortunately, the
development of antibiotic resistance threatens our current therapeutic arsenal, which has …

Processing of next-generation sequencing (NGS) data requires significant technical skills,
involving installation, configuration, and execution of bioinformatics data pipelines, in addition …

High mortality rates of prostate cancer (PCa) are associated with metastatic castration-resistant
prostate cancer (CRPC) due to the maintenance of androgen receptor (AR) signaling …

The human microbiota plays a critical role in host health. Proper development of the infant
microbiome is particularly important. Its dysbiosis leads to both short-term health issues and …

Background Metagenomic shotgun sequencing is becoming increasingly popular to study
microbes associated with the human body and in environmental samples. A key goal of …

Motivation: Given the abundance of genome sequencing and omics data, an opprtunity and
challenge in bioinformatics relates to data mining and visualization. The majority of current …

Prostate cancer is the second most commonly diagnosed male cancer in the world. The
molecular mechanisms underlying its development and progression are still unclear. Here we …