Glioblastoma (GBM) is a hypervascular neoplasia of the central nervous system with an
extremely high rate of mortality. Owing to its hypervascularity, anti-angiogenic therapies (AAT) …

Exosomes are critical mediators of intercellular crosstalk and are regulator of the cellular/tumor
microenvironment. Exosomes have great prospects for clinical application as a …

Metastatic breast cancer (BC) (also referred to as stage IV) spreads beyond the breast to the
bones, lungs, liver, or brain and is a major contributor to the deaths of cancer patients. …

BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed
therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven …

Glioblastoma (GBM) is one hypervascular and hypoxic tumor known among solid tumors.
Antiangiogenic therapeutics (AATs) have been tested as an adjuvant to normalize blood …

Myeloid‑derived suppressor cells (MDSCs) are an indispensable component of the tumor
microenvironment (TME). Along with the role of MDSC immunosuppression and antitumor …

Melatonin, a hormone secreted by pineal gland, exerts antimetastatic effects by reducing
tumor cell proliferation, migration and invasion. MicroRNAs (miRNAs) are small, non-coding …

Tumor development and therapeutic resistance are linked with tumor-associated macrophage
(TAM) and myeloid-derived suppressor cell (MDSC) infiltration in tumors via chemokine …

… Kartik Angara searched the recent references and wrote the section on tumor microenvironment
and challenges of alternative vascularization in GBM; Thaiz F. Borin searched the recent …

Glioblastoma (GBM) is a hypervascular and aggressive primary malignant tumor of the
central nervous system. Recent investigations showed that traditional therapies along with …