Adult epidermal development in Drosophila showcases a striking balance between en
masse spreading of the developing adult precursor tissues and retraction of the degenerating …

Huntington’s disease (HD) is a genetic disorder caused by a CAG expansion mutation in
the huntingtin gene leading to polyglutamine (polyQ) expansion in the N-terminal part of …

Morphogen gradients provide essential positional information to gene networks through their
spatially heterogeneous distribution, yet how they form is still hotly contested, with multiple …

Huntington’s disease (HD) is a neurodegenerative disorder induced by aggregation of the
pathological form of Huntingtin protein that has expanded polyglutamine (polyQ) repeats. In …

Spatiotemporal changes in epithelial cell sizes—or epithelial cell size dynamics (ECD)—during
morphogenesis entail interplay between two opposing forces: cell contraction via …

Imaging fluorescence correlation spectroscopy (FCS) is a powerful tool to extract information
on molecular mobilities, actions, and interactions in live cells, tissues, and organisms. …

Imaging Fluorescence Correlation Spectroscopy (Imaging FCS) is a powerful tool to extract
information on molecular mobilities, actions and interactions in live cells, tissues and …

During tissue closures, such as embryonic dorsal closure in Drosophila melanogaster, a
proximate extra-embryonic layer, amnioserosa, generates forces that drive migration of the …

Adult thorax formation in Drosophila begins during pre-pupal development by fusion of its
two contralateral progenitor halves, the heminotal epithelia (HE). HEs migrate and replace an …

Cancer resistance varies amongst individuals: however, its host genetic underpinnings
remain elusive. Here we show that host genetically induced systemic Toll signaling confers …