V-ATPases are membrane-embedded protein complexes that function as ATP hydrolysis-driven
proton pumps. V-ATPases are the primary source of organellar acidification in all …

Vacuolar-type ATPases (V-ATPases) are rotary enzymes that acidify intracellular compartments
in eukaryotic cells. These multi-subunit complexes consist of a cytoplasmic V 1 region …

Proton-translocating vacuolar-type ATPases (V-ATPases) are necessary for numerous
processes in eukaryotic cells, including receptor-mediated endocytosis, protein maturation, and …

Mutations in Ras family proteins are implicated in 33% of human cancers, but direct
pharmacological inhibition of Ras mutants remains challenging. As an alternative to direct inhibition, …

Vacuolar-type ATPases (V-ATPases) are membrane protein complexes that function as proton
pumps. V-ATPases acidify the intracellular compartments of all eukaryotic cells, making …

Mutations in the Ras family of oncogenes are implicated in 33% of human cancers, making
Ras an intensely pursued target in drug discovery. As an alternative to direct …

The crop pest Drosophila suzukii, native to Southeast Asia, has been found in Ontario since
2010. This raises concern with respect to it establishing permanent populations, however, …

The type IVa pilus system can be used for adhesion, natural competence, phage adsorption,
folded-protein secretion, surface sensing, and surface associated motility. Likewise, it is a …

… We thank Stephanie Bueler with assistance in generating the ySCB1 yeast strain and
Thamiya Vasanthakumar and Zev Ripstein for helpful discussions regarding ATPase assays and …

Drosophila suzukii (Matsumura) (Diptera: Drosophilidae) is a worldwide emerging pest of
soft fruits, but its cold tolerance has not been thoroughly explored. We determined the cold …