Made by cells for cells–extracellular vesicles as next-generation mainstream medicines
Current medicine has only taken us so far in reducing disease and tissue damage. Extracellular
vesicles (EVs), which are membranous nanostructures produced naturally by cells, have …
vesicles (EVs), which are membranous nanostructures produced naturally by cells, have …
Placenta stem/stromal cell–derived extracellular vesicles for potential use in lung repair
Many acute and chronic lung injuries are incurable and rank as the fourth leading cause of
death globally. While stem cell treatment for lung injuries is a promising approach, there is …
death globally. While stem cell treatment for lung injuries is a promising approach, there is …
Advanced pathophysiology mimicking lung models for accelerated drug discovery
Background Respiratory diseases are the 2nd leading cause of death globally. The current
treatments for chronic lung diseases are only supportive. Very few new classes of …
treatments for chronic lung diseases are only supportive. Very few new classes of …
[HTML][HTML] New multiscale characterization methodology for effective determination of isolation–structure–function relationship of extracellular vesicles
TH Phan, SK Divakarla, JH Yeo, Q Lei… - … in Bioengineering and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) have been lauded as next-generation medicines, but very few
EV-based therapeutics have progressed to clinical use. Limited clinical translation is largely …
EV-based therapeutics have progressed to clinical use. Limited clinical translation is largely …
[HTML][HTML] Extracellular vesicles as next-generation therapeutics and biomarkers in amyloidosis: a new frontier
TH Phan, JH Reed - Frontiers in Biomaterials Science, 2024 - frontiersin.org
Nanoparticles hold a great potential for therapeutic targeting due to their ability to improve
the stability of encapsulated cargo and promote the transport of cargo across membranes to …
the stability of encapsulated cargo and promote the transport of cargo across membranes to …
Positively charged gold–silver nanostar enabled molecular characterization of cancer associated extracellular vesicles
Y Liu, W Zhang, TH Phan, W Chrzanowski… - Analytical …, 2020 - pubs.rsc.org
Direct surface-enhanced Raman scattering (SERS) has contributed to characterizing
extracellular vesicles (EVs) by providing molecular signatures. However, little work has been …
extracellular vesicles (EVs) by providing molecular signatures. However, little work has been …
[HTML][HTML] Extracellular Vesicle-Based Coatings Enhance Bioactivity of Titanium Implants—SurfEV
Extracellular vesicles (EVs) are nanoparticles released by cells that contain a multitude of
biomolecules, which act synergistically to signal multiple cell types. EVs are ideal candidates …
biomolecules, which act synergistically to signal multiple cell types. EVs are ideal candidates …
Factors affecting the management of public agricultural land fund in Gia Lam District, Hanoi City, Vietnam
The study aims to identify the influencing factors and their impact level on the public agricultural
land management. The results show that the policy group is the most influential with an …
land management. The results show that the policy group is the most influential with an …
Dual Emission Carbon Dots for Simultaneous Detections of Pb2+ and Fe3+ Ions in Water Via Distinct Sensing Mechanisms
Herein, dual-emission carbon dots (DE-CDs) were synthesized using a one-pot hydrothermal
method. DE-CDs exhibited two well-separated peaks at 433 and 513 nm under ultraviolet …
method. DE-CDs exhibited two well-separated peaks at 433 and 513 nm under ultraviolet …
A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4
Defensins are key components of both innate and adaptive immune responses to pathogens.
Cryptdins are mouse alpha‐defensins that are secreted from Paneth cells in the small …
Cryptdins are mouse alpha‐defensins that are secreted from Paneth cells in the small …