User profiles for Thea K. Schulze

Thea K. Schulze

University of Copenhagen
Verified email at bio.ku.dk
Cited by 145

Accurate model of liquid–liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties

G Tesei, TK Schulze, R Crehuet… - Proceedings of the …, 2021 - National Acad Sciences
Many intrinsically disordered proteins (IDPs) may undergo liquid–liquid phase separation (LLPS)
and participate in the formation of membraneless organelles in the cell, thereby …

[HTML][HTML] Characterizing glucokinase variant mechanisms using a multiplexed abundance assay

S Gersing, TK Schulze, M Cagiada, A Stein, FP Roth… - Genome Biology, 2024 - Springer
Amino acid substitutions can perturb protein activity in multiple ways. Understanding their
mechanistic basis may pinpoint how residues contribute to protein function. Here, we …

Deep mutational scanning reveals a tight correlation between protein degradation and toxicity of thousands of non-native aspartoacylase protein variants

…, V Voutsinos, KE Johansson, TK Schulze… - bioRxiv, 2023 - biorxiv.org
When the structural stability of a protein is compromised, the protein may form non-native
interactions with other cell proteins and thus becomes a hazard to the cell. To mitigate this …

Influence of anatomic conditions on efficacy and safety of combined intermediate cervical plexus block and perivascular infiltration of internal carotid artery in carotid …

…, S Ludwig, C Reeps, AR Heller, K Thea… - Ultrasound in Medicine …, 2021 - Elsevier
Ultrasound-guided intermediate cervical plexus blockade with perivascular infiltration of the
carotid artery bifurcation perivacular block (PVB) is a reliable technique for regional …

[PDF][PDF] Accurate model of liquid-liquid phase behaviour of intrinsically-disordered proteins from data-driven optimization of single-chain properties

G Tesei, TK Schulze, R Crehuet, K Lindorff-Larsen - bioRxiv, 2021 - scholar.archive.org
Many intrinsically disordered proteins (IDPs) may undergo liquidliquid phase separation (LLPS)
and participate in the formation of membraneless organelles in the cell, thereby …

Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis

…, R Lukowski, F Essmann, K Schulze-Osthoff… - Circulation …, 2014 - Am Heart Assoc
Rationale: Atherosclerosis is a widespread and devastating disease, but the origins of cells
within atherosclerotic plaques are not well defined. Objective: To investigate the specific …

[HTML][HTML] Foveal and Peripapillary Choroidal Thickness in Adults Born Extremely, Very, and Moderately Preterm With and Without ROP–Results From the Gutenberg …

A Fieß, K Schulze, SD Grabitz, S Gißler… - … Vision Science & …, 2022 - iovs.arvojournals.org
… Kai Schulze … This study contains parts of the thesis of Kai Schulze. … Pfeiffer, Novartis (F),
Ivantis (F), Santen (F), Thea (F), Boehringer Ingelheim Deutschland GmbH & Co. KG (F), Alcon (F)…

[HTML][HTML] The global land water storage data set release 2 (GLWS2. 0) derived via assimilating GRACE and GRACE-FO data into a global hydrological model

H Gerdener, J Kusche, K Schulze, P Döll, A Klos - Journal of Geodesy, 2023 - Springer
We describe the new global land water storage data set GLWS2.0, which contains total water
storage anomalies (TWSA) over the global land except for Greenland and Antarctica with a …

[HTML][HTML] Potentials and pitfalls of DNA array analysis of the endothelial stress response

D Viemann, K Schulze-Osthoff, J Roth - Biochimica et Biophysica Acta (BBA …, 2005 - Elsevier
Endothelial cells respond to inflammatory stimuli with complex genetic alterations that determine
the immune response and the outcome of the inflammatory process. An additional layer …

Search for Evidence of the Type-III Seesaw Mechanism in Multilepton Final States in Proton-Proton Collisions at = 13 TeV

…, D Pinna, G Rauco, D Salerno, K Schweiger… - Physical Review …, 2017 - zora.uzh.ch
A search for a signal consistent with the type-III seesaw mechanism in events with three or
more electrons or muons is presented. The data sample consists of proton-proton collisions at …