User profiles for Theo Bestebroer

Theo Bestebroer

Verified email at erasmusmc.nl
Cited by 31135

[HTML][HTML] Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

…, S Van Boheemen, TM Bestebroer… - … England Journal of …, 2012 - Mass Medical Soc
<p id="p001">A previously unknown coronavirus was isolated from the sputum of a 60-year-old
man who presented with acute pneumonia and subsequent renal failure with a fatal …

Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls

…, V Munster, A Wallensten, TM Bestebroer… - Journal of …, 2005 - Am Soc Microbiol
In wild aquatic birds and poultry around the world, influenza A viruses carrying 15 antigenic
subtypes of hemagglutinin (HA) and 9 antigenic subtypes of neuraminidase (NA) have been …

Mapping the antigenic and genetic evolution of influenza virus

DJ Smith, AS Lapedes, JC De Jong, TM Bestebroer… - science, 2004 - science.org
The antigenic evolution of influenza A (H3N2) virus was quantified and visualized from its
introduction into humans in 1968 to 2003. Although there was remarkable correspondence …

Airborne transmission of influenza A/H5N1 virus between ferrets

…, E De Wit, VJ Munster, EM Sorrell, TM Bestebroer… - science, 2012 - science.org
Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans
but thus far has not acquired the ability to be transmitted by aerosol or respiratory droplet (“…

Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

…, M De Graaf, C Lauber, TM Bestebroer… - MBio, 2012 - Am Soc Microbiol
A novel human coronavirus (HCoV-EMC/2012) was isolated from a man with acute pneumonia
and renal failure in June 2012. This report describes the complete genome sequence, …

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

B Rockx, T Kuiken, S Herfst, T Bestebroer, MM Lamers… - Science, 2020 - science.org
The current pandemic coronavirus, severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2),
was recently identified in patients with an acute respiratory syndrome, coronavirus …

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

…, S Van Nieuwkoop, TM Bestebroer… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Coronaviruses can cause respiratory and enteric disease in a wide variety of human and
animal hosts. The 2003 outbreak of severe acute respiratory syndrome (SARS) first …

[HTML][HTML] SARS-CoV-2 is transmitted via contact and via the air between ferrets

M Richard, A Kok, D de Meulder, TM Bestebroer… - Nature …, 2020 - nature.com
SARS-CoV-2, a coronavirus that emerged in late 2019, has spread rapidly worldwide, and
information about the modes of transmission of SARS-CoV-2 among humans is critical to …

A previously undescribed coronavirus associated with respiratory disease in humans

…, NG Hartwig, TM Bestebroer… - Proceedings of the …, 2004 - National Acad Sciences
The etiology of acute respiratory tract illnesses is sometimes unclear due to limitations of
diagnostic tests or the existence of as-yet-unidentified pathogens. Here we describe the …

Pathogenesis and transmission of swine-origin 2009 A (H1N1) influenza virus in ferrets

…, S Herfst, EJA Schrauwen, TM Bestebroer… - Science, 2009 - science.org
The swine-origin A(H1N1) influenza virus that has emerged in humans in early 2009 has
raised concerns about pandemic developments. In a ferret pathogenesis and transmission …