Prediction of total genetic value using genome-wide dense marker maps

THE Meuwissen, BJ Hayes, ME Goddard - genetics, 2001 - academic.oup.com
Recent advances in molecular genetic techniques will make dense marker maps available
and genotyping many individuals for these markers feasible. Here we attempted to estimate …

Fine-mapping inflammatory bowel disease loci to single-variant resolution

…, CW Lees, E Louis, R Mariman, T Meuwissen… - Nature, 2017 - nature.com
Inflammatory bowel diseases are chronic gastrointestinal inflammatory disorders that affect
millions of people worldwide. Genome-wide association studies have identified 200 …

Genomic selection: a paradigm shift in animal breeding

T Meuwissen, B Hayes, M Goddard - Animal frontiers, 2016 - academic.oup.com
Traditional marker-assisted selection (MAS) did not result in a widespread use of DNA
information in animal breeding. The main reason was that the traits of interest in livestock …

Accurate prediction of genetic values for complex traits by whole-genome resequencing

T Meuwissen, M Goddard - Genetics, 2010 - academic.oup.com
Whole-genome resequencing technology has improved rapidly during recent years and is
expected to improve further such that the sequencing of an entire human genome sequence …

Using the genomic relationship matrix to predict the accuracy of genomic selection

…, BJ Hayes, THE Meuwissen - Journal of animal …, 2011 - Wiley Online Library
Estimated breeding values (EBVs) using data from genetic markers can be predicted using
a genomic relationship matrix, derived from animal’s genotypes, and best linear unbiased …

Accelerating improvement of livestock with genomic selection

T Meuwissen, B Hayes, M Goddard - Annu. Rev. Anim. Biosci., 2013 - annualreviews.org
Three recent breakthroughs have resulted in the current widespread use of DNA information:
the genomic selection (GS) methodology, which is a form of marker-assisted selection on a …

The accuracy of genomic selection in Norwegian red cattle assessed by cross-validation

…, S Lien, M Kent, M Svendsen, THE Meuwissen - Genetics, 2009 - academic.oup.com
Genomic Selection (GS) is a newly developed tool for the estimation of breeding values for
quantitative traits through the use of dense markers covering the whole genome. For a …

[HTML][HTML] Accuracy of breeding values of'unrelated'individuals predicted by dense SNP genotyping

THE Meuwissen - Genetics Selection Evolution, 2009 - Springer
Background Recent developments in SNP discovery and high throughput genotyping
technology have made the use of high-density SNP markers to predict breeding values feasible. …

[HTML][HTML] Testing strategies for genomic selection in aquaculture breeding programs

AK Sonesson, THE Meuwissen - Genetics Selection Evolution, 2009 - Springer
Background Genomic selection is a selection method where effects of dense genetic
markers are first estimated in a test population and later used to predict breeding values of …

Prediction of identity by descent probabilities from marker-haplotypes

THE Meuwissen, ME Goddard - Genetics Selection Evolution, 2001 - Springer
The prediction of identity by descent (IBD) probabilities is essential for all methods that map
quantitative trait loci (QTL). The IBD probabilities may be predicted from marker genotypes …