Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma
proteome. Here we report a highly parallel protein quantitation platform integrating …

Deep interrogation of plasma proteins on a large scale is a challenge due to the number
and concentration of proteins, which span a dynamic range of over 10 orders of magnitude. …

Comprehensive assessment of the human proteome remains challenging due to multiple
forms of a protein, or proteoforms, arising from alternative splicing, allelic variation, and protein …

Advancements in deep plasma proteomics are enabling high-resolution measurement of
plasma proteoforms, which may reveal a rich source of novel biomarkers previously concealed …

… Thomas Collier Platt of New York was selected for this analysis because there is a wealth of
… at the time when Theodore Roosevelt was coming into national notice. Platt's relations with …

To geographers and their fellow travelers, there are few greater treats than to fly a
considerable distance over land on a clear day with a view unobstructed by the airplane wing. I …

Introduction: Our ~20,000 genes encode over ~1 million protein variants because of alternative
splice forms, allelic variation and protein modification. Large-scale genomics studies …

This Handbook is the first to explore the emergent field of ‘placemaking’in terms of the
recent research, teaching and learning, and practice agenda for the next few years. Offering …

… One oral practice was permitted, and if the subject could not read the passage spontaneously,
the experimenter modelled short phrases which the subject then repeated. Intelligibility of …

Background New WHO guidelines recommend initiation of antiretroviral therapy for HIV-positive
adults with CD4 counts of 500 cells per μL or less, a higher threshold than was …