Genotypic differences greatly influence susceptibility and resistance to disease.
Understanding genotype–phenotype relationships requires that phenotypes be viewed as …

Some hospitals test all patients for SARS-CoV-2 infection on admission to prevent transmission
from patients with unrecognized infection to staff and other patients, since two-thirds of …

Chikungunya virus ( CHIKV ) is a mosquito‐borne alphavirus that causes global epidemics
of debilitating disease worldwide. To gain functional insight into the host cellular genes …

Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when
treatment conditions are optimal according to experimental protocols. Adapted subclones, …

Background Influential studies conclude that each hour until antibiotics increases mortality
in sepsis. However, these analyses often (1) adjusted for limited covariates, (2) included …

Background Sepsis, defined as a dysregulated host response to infection leading to acute
organ dysfunction, affects millions of patients per year. It is associated with 850,000 visits to …

Recent reviews have examined the extent to which routine next-generation sequencing (NGS)
on clinical specimens will improve the capabilities of clinical microbiology laboratories in …

Dengue virus (DENV) is the most prevalent mosquito-borne virus causing human disease.
Of the 4 DENV serotypes, epidemiological data suggest that DENV-2 secondary infections …

Background Nosocomial respiratory virus outbreaks represent serious public hgealth
challenges. Rapid and precise identification of cases and tracing of transmission chains is critical …

Whole-genome sequencing (WGS) of Staphylococcus aureus is increasingly used as part of
infection prevention practices. In this study, we established a long-read technology-based …