The clearance of untranslated mRNAs by Argonaute proteins is essential for embryonic
development in metazoans. However, it is currently unknown whether similar processes exist in …

In animal germlines, transposons are silenced at the transcriptional or post-transcriptional
level to prevent deleterious expression. Ciliates employ a more direct approach by physically …

Most eukaryotes employ a combination of transcriptional and post-transcriptional silencing
mechanisms to suppress transposons, yet ciliates employ a more extreme approach. They …

The formation of resting cysts commonly found in unicellular eukaryotes is a complex and
highly regulated survival strategy against environmental stress that involves drastic …

The development of immune checkpoint inhibitors represents a major breakthrough in
cancer therapy. Nevertheless, a substantial number of patients fail to respond to checkpoint …

Small RNAs mediate the silencing of transposable elements and other genomic loci, increasing
nucleosome density and preventing undesirable gene expression. The unicellular ciliate …

Unicellular eukaryotes represent tremendous evolutionary diversity. However, the molecular
mechanisms underlying this diversity remain largely unexplored, partly due to a limitation of …

Small RNAs are known to mediate silencing of transposable elements and other genomic
loci, increasing nucleosome density and preventing undesirable gene expression. Post-…

A major challenge for successful cultured meat production is the requirement for large
quantities of skeletal muscle satellite cells (MuSCs). Commercial microcarriers (MCs), such as …

Collagen is extensively used in fabrication of hydrogels for biomedical applications but
needs improvement after its isolation from tissues due to slow gelation and poor mechanical …