Efficient ancestry and mutation simulation with msprime 1.0

…, MF Rodrigues, K Saunack, T Sellinger… - Genetics, 2022 - academic.oup.com
Stochastic simulation is a key tool in population genetics, since the models involved are
often analytically intractable and simulation is usually the only way of obtaining ground-truth …

[HTML][HTML] Inference of past demography, dormancy and self-fertilization rates from whole genome sequence data

TPP Sellinger, D Abu Awad, M Moest, A Tellier - PLoS Genetics, 2020 - journals.plos.org
Several methods based on the Sequential Markovian coalescence (SMC) have been developed
that make use of genome sequence data to uncover population demographic history, …

Are the better cooperators dormant or quiescent?

T Sellinger, J Müller, V Hösel, A Tellier - Mathematical biosciences, 2019 - Elsevier
Despite the wealth of empirical and theoretical studies, the origin and maintenance of
cooperation is still an evolutionary riddle. In this context, ecological life-history traits which affect …

Determinants of rapid adaptation in species with large variance in offspring production

K Korfmann, M Temple‐Boyer, T Sellinger… - Molecular …, 2023 - Wiley Online Library
The speed of population adaptation to changing biotic and abiotic environments is determined
by the interaction between genetic drift, positive selection and linkage effects. Many …

Joint inference of evolutionary transitions to self-fertilization and demographic history using whole-genome sequences

S Strütt, T Sellinger, S Glémin, A Tellier, S Laurent - Elife, 2023 - elifesciences.org
The evolution from outcrossing to selfing occurred recently across the eukaryote tree of life
in plants, animals, fungi, and algae. Despite short-term advantages, selfing is hypothetically …

Limits and convergence properties of the sequentially Markovian coalescent

TPP Sellinger, D Abu‐Awad… - Molecular Ecology …, 2021 - Wiley Online Library
Several methods based on the sequentially Markovian coalescent (SMC) make use of full
genome sequence data from samples to infer population demographic history including past …

[HTML][HTML] Simultaneous inference of past demography and selection from the ancestral recombination graph under the beta coalescent

K Korfmann, TPP Sellinger, F Freund… - Peer Community …, 2024 - peercommunityjournal.org
The reproductive mechanism of a species is a key driver of genome evolution. The standard
Wright-Fisher model for the reproduction of individuals in a population assumes that each …

[HTML][HTML] Correction: Inference of past demography, dormancy and self-fertilization rates from whole genome sequence data

TPP Sellinger, D Abu Awad, M Moest, A Tellier - PLoS Genetics, 2021 - journals.plos.org
The mutation and recombination rates reported throughout the article are incorrect by a factor
of 2. The captions of Figs 1–4, Table 2, and S1–S19 Figs are incorrect. Additionally, the Y …

Improved inference of population histories by integrating genomic and epigenomic data

T Sellinger, F Johannes, A Tellier - bioRxiv, 2023 - biorxiv.org
With the availability of high quality full genome polymorphism (SNPs) data, it becomes
feasible to study the past demographic and selective history of populations in exquisite detail. …

Inference of evolutionary transitions to self-fertilization using whole-genome sequences

S Struett, T Sellinger, S Glémin, A Tellier, S Laurent - bioRxiv, 2022 - biorxiv.org
The evolution from outcrossing to selfing is a transition that occurred recurrently throughout
the eukaryote tree of life, in plants, animals, fungi and algae. Despite some short-term …