Metabolic endotoxemia initiates obesity and insulin resistance
…, C Chabo, A Waget, E Delmée, B Cousin, T Sulpice… - Diabetes, 2007 - Am Diabetes Assoc
Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a
low-grade inflammation. Seeking an inflammatory factor causative of the onset of insulin …
low-grade inflammation. Seeking an inflammatory factor causative of the onset of insulin …
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
…, N Smirnova, M Bergé, T Sulpice… - EMBO molecular …, 2011 - embopress.org
A fat‐enriched diet modifies intestinal microbiota and initiates a low‐grade inflammation,
insulin resistance and type‐2 diabetes. Here, we demonstrate that before the onset of diabetes, …
insulin resistance and type‐2 diabetes. Here, we demonstrate that before the onset of diabetes, …
[HTML][HTML] Artemisinins target GABAA receptor signaling and impair α cell identity
Type 1 diabetes is characterized by the destruction of pancreatic β cells, and generating new
insulin-producing cells from other cell types is a major aim of regenerative medicine. One …
insulin-producing cells from other cell types is a major aim of regenerative medicine. One …
[HTML][HTML] Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass
…, E Mouisel, C Thalamas, N Viguerie, T Sulpice… - PLoS …, 2013 - journals.plos.org
When energy is needed, white adipose tissue (WAT) provides fatty acids (FAs) for use in
peripheral tissues via stimulation of fat cell lipolysis. FAs have been postulated to play a critical …
peripheral tissues via stimulation of fat cell lipolysis. FAs have been postulated to play a critical …
Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice
…, J Castel, C Garret, G Payros, A Maida, T Sulpice… - …, 2011 - academic.oup.com
Inhibition of dipeptidyl peptidase-4 (DPP-4) activity improves glucose homeostasis through
a mode of action related to the stabilization of the active forms of DPP-4-sensitive hormones …
a mode of action related to the stabilization of the active forms of DPP-4-sensitive hormones …
Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters
…, V Richard, J Dubuisson, C Grangette, T Sulpice… - Gut …, 2022 - Taylor & Francis
Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral
infections. We herein hypothesized that disruption of gut homeostasis during severe acute …
infections. We herein hypothesized that disruption of gut homeostasis during severe acute …
Empagliflozin, via switching metabolism toward lipid utilization, moderately increases LDL cholesterol levels through reduced LDL catabolism
…, N Burr, I Urbain, C Costard, M Mark, T Sulpice - Diabetes, 2016 - Am Diabetes Assoc
In clinical trials, a small increase in LDL cholesterol has been reported with sodium–glucose
cotransporter 2 (SGLT2) inhibitors. The mechanisms by which the SGLT2 inhibitor …
cotransporter 2 (SGLT2) inhibitors. The mechanisms by which the SGLT2 inhibitor …
Role of peripheral benzodiazepine receptors in mitochondrial, cellular, and cardiac damage induced by oxidative stress and ischemia-reperfusion
N Leducq, F Bono, T Sulpice, V érie Vin, P Janiak… - … of Pharmacology and …, 2003 - ASPET
Mitochondrial dysfunction has been identified as a possible early event in ischemia-reperfusion
damage. The peripheral benzodiazepine receptor, a mitochondrial inner membrane …
damage. The peripheral benzodiazepine receptor, a mitochondrial inner membrane …
[HTML][HTML] Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters
…, V Shah, RJ Vreeken, T Hankemeier, T Sulpice… - Journal of lipid …, 2011 - ASBMB
Cholesteryl ester transfer protein (CETP) transfers cholesteryl ester (CE) and triglyceride
between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of …
between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of …
Anti-hyperglycaemic and anti-obesity effects of Capparis spinosa and Chamaemelum nobile aqueous extracts in HFD mice.
A Lemhadri, M Eddouks, T Sulpice, R Burcelin - 2007 - cabidigitallibrary.org
This study was undertaken in order to evaluate the possible anti-hyperglycaemic and body
weight reducing activities of the aqueous extract of both Capparis spinosa (CS) and …
weight reducing activities of the aqueous extract of both Capparis spinosa (CS) and …