User profiles for Thomas Childs
Thomas ChildsUniversity College London Verified email at ucl.ac.uk Cited by 98 |
[BOOK][B] Metal machining: theory and applications
THC Childs - 2000 - books.google.com
Metal machining is the most widespread metal-shaping process in the mechanical manufacturing
industry. World-wide investment in metal machining tools increases year on year-and …
industry. World-wide investment in metal machining tools increases year on year-and …
[HTML][HTML] Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease
Alzheimer’s disease (AD) is characterized by synaptic loss, which can result from
dysfunctional microglial phagocytosis and complement activation. However, what signals drive …
dysfunctional microglial phagocytosis and complement activation. However, what signals drive …
[HTML][HTML] Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project
…, AC Ramos, D Cheillan, YH Chien, TA Childs… - Genetics in …, 2011 - nature.com
Purpose: To achieve clinical validation of cutoff values for newborn screening by tandem mass
spectrometry through a worldwide collaborative effort. Methods: Cumulative percentiles of …
spectrometry through a worldwide collaborative effort. Methods: Cumulative percentiles of …
Minimising Embodied Product Energy to support energy efficient manufacturing
S Rahimifard, Y Seow, T Childs - CIRP annals, 2010 - Elsevier
Green sources of power generation and efficient management of energy demand are among
the greatest challenges facing manufacturing businesses. A significant proportion of energy …
the greatest challenges facing manufacturing businesses. A significant proportion of energy …
GSK-3β negatively regulates skeletal myotube hypertrophy
…, TW Abraha, TE Childs… - … of Physiology-Cell …, 2002 - journals.physiology.org
To determine whether changes in glycogen synthase kinase-3β (GSK-3β) phosphorylation
contribute to muscle hypertrophy, we delineated the effects of GSK-3β activity on C 2 C 12 …
contribute to muscle hypertrophy, we delineated the effects of GSK-3β activity on C 2 C 12 …
Microglia‐synapse engulfment via PtdSer‐TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models
…, D Sokolova, SE Lee, T Childs… - The EMBO …, 2023 - embopress.org
Neuronal hyperactivity is a key feature of early stages of Alzheimer's disease (AD). Genetic
studies in AD support that microglia act as potential cellular drivers of disease risk, but the …
studies in AD support that microglia act as potential cellular drivers of disease risk, but the …
[HTML][HTML] Enhanced interpretation of newborn screening results without analyte cutoff values
…, M Sierra, YH Chien, WL Hwu, T Childs… - Genetics in …, 2012 - nature.com
Purpose: To improve quality of newborn screening by tandem mass spectrometry with a novel
approach made possible by the collaboration of 154 laboratories in 49 countries. Methods…
approach made possible by the collaboration of 154 laboratories in 49 countries. Methods…
Temporal alterations in protein signaling cascades during recovery from muscle atrophy
TE Childs, EE Spangenburg… - American Journal of …, 2003 - journals.physiology.org
Currently, the repertoire of cellular and molecular pathways that control skeletal muscle atrophy
and hypertrophy are not well defined. It is possible that intracellular regulatory signaling …
and hypertrophy are not well defined. It is possible that intracellular regulatory signaling …
Exploring relationships between touch perception and surface physical properties
This paper reports a study of materials for confectionery packaging. The aim was to explore
the touch perceptions of textures and identify their relationships with the surfaces' physical …
the touch perceptions of textures and identify their relationships with the surfaces' physical …
Dopamine D1 receptor modulation in nucleus accumbens lowers voluntary wheel running in rats bred to run high distances
Dopamine signaling in the nucleus accumbens (NAc) has been postulated to influence reward
development towards drugs of abuse and exercise. Herein, we used generation 4–5 rats …
development towards drugs of abuse and exercise. Herein, we used generation 4–5 rats …