Malignant mesothelioma (MM) is an aggressive cancer primarily diagnosed on the basis of
histological criteria 1 . The 2015 World Health Organization classification subdivides …

Although aberrant DNA methylation patterning is a hallmark of cancer, the relevance of
targeting DNA methyltransferases (DNMT) remains unclear for most tumors. In diffuse large B-…

Deep learning methods for digital pathology analysis are an effective way to address multiple
clinical questions, from diagnosis to prediction of treatment outcomes. These methods …

Can traditional computational analysis and machine learning help compensate for
inadequate peer review of drug-repurposing papers in the context of an infodemic?

The SARS-COV-2 pandemic has put pressure on intensive care units, so that identifying
predictors of disease severity is a priority. We collect 58 clinical and biological variables, and …

What's known on the subject? and What does the study add? Radical nephroureterectomy (
RNU ), the standard of care treatment for high‐risk urothelial carcinoma of the upper tract ( …

Background and Aims Standardized and robust risk‐stratification systems for patients with
hepatocellular carcinoma (HCC) are required to improve therapeutic strategies and …

Bladder cancer is among the five most common cancers diagnosed in the Western world and
causes significant mortality and morbidity rates in affected patients. Therapeutic options to …

The phenotype of germinal center (GC) B cells includes the unique ability to tolerate rapid
proliferation and the mutagenic actions of activation induced cytosine deaminase (AICDA). …

Background There is a lack of consensus regarding the optimal approach to the bladder cuff
during radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). …