User profiles for Thomas D. Brekke

Thomas D Brekke

Bangor University
Verified email at bangor.ac.uk
Cited by 227

Inbred or outbred? Genetic diversity in laboratory rodent colonies

TD Brekke, KA Steele, JF Mulley - G3: Genes, Genomes …, 2018 - academic.oup.com
Nonmodel rodents are widely used as subjects for both basic and applied biological
research, but the genetic diversity of the study individuals is rarely quantified. University-housed …

Defensive endosymbionts: a cryptic trophic level in community ecology

J Jaenike, TD Brekke - Ecology letters, 2011 - Wiley Online Library
… Here, we show that Spiroplasma spreads rapidly within experimental populations of D.
neotestacea subject to Howardula parasitism, but is neither strongly favored nor selected against …

A new chromosome-assigned Mongolian gerbil genome allows characterization of complete centromeres and a fully heterochromatic chromosome

TD Brekke, AST Papadopulos, E Julià… - Molecular Biology …, 2023 - academic.oup.com
Chromosome-scale genome assemblies based on ultralong-read sequencing technologies
are able to illuminate previously intractable aspects of genome biology such as fine-scale …

Parent-of-origin growth effects and the evolution of hybrid inviability in dwarf hamsters

TD Brekke, JM Good - Evolution, 2014 - academic.oup.com
Mammalian hybrids often show abnormal growth, indicating that developmental inviability
may play an important role in mammalian speciation. Yet, it is unclear if this recurrent …

Genomic imprinting, disrupted placental expression, and speciation

TD Brekke, LA Henry, JM Good - Evolution, 2016 - academic.oup.com
The importance of regulatory incompatibilities to the early stages of speciation remains
unclear. Hybrid mammals often show extreme parent-of-origin growth effects that are thought to …

X chromosome-dependent disruption of placental regulatory networks in hybrid dwarf hamsters

TD Brekke, EC Moore, SC Campbell-Staton… - Genetics, 2021 - academic.oup.com
Thomas D Brekke and Emily C Moore authors contributed equally to this work. … candidate
imprinted genes (Brekke et al. 2016) showing maternally biased expression (D; total genes, N …

[HTML][HTML] QTL mapping in salad tomatoes

TD Brekke, JA Stroud, DS Shaw, S Crawford, KA Steele - Euphytica, 2019 - Springer
Tomatoes are a major global food staple but Phytophthora infestans (an Oomycete) causes
late-blight, a devastating disease that precludes commercial tomato production from moist …

[HTML][HTML] A high-density genetic map and molecular sex-typing assay for gerbils

TD Brekke, S Supriya, MG Denver, A Thom… - Mammalian …, 2019 - Springer
We constructed a high-density genetic map for Mongolian gerbils (Meriones unguiculatus).
We genotyped 137 F2 individuals with a genotype-by-sequencing (GBS) approach at over …

[HTML][HTML] Shed skin as a source of DNA for genotyping-by-sequencing (GBS) in reptiles

TD Brekke, L Shier, MJ Hegarty, JF Mulley - Conservation Genetics …, 2023 - Springer
Over a fifth of reptile species are classified as ‘Threatened’ and conservation efforts, especially
those aimed at recovery of isolated or fragmented populations, will require genetic and …

Sequence features do not drive karyotypic evolution: what are the missing correlates of genome evolution?

TD Brekke, AST Papadopulos, MT Swain, JF Mulley - bioRxiv, 2022 - biorxiv.org
Genome rearrangements are prevalent across the tree of life and even within species. After
two decades of research, various suggestions have been proposed to explain which features …