The ability to produce stem cells by induced pluripotency (iPS reprogramming) has
rekindled an interest in earlier studies showing that transcription factors can directly convert …

The proton is the primary building block of the visible Universe, but many of its properties—such
as its charge radius and its anomalous magnetic moment—are not well understood. The …

Starting with multipotent progenitors, hematopoietic lineages are specified by lineage-restricted
transcription factors. The transcription factors that determine the decision between …

Accurate knowledge of the charge and Zemach radii of the proton is essential, not only for
understanding its structure but also as input for tests of bound-state quantum electrodynamics …

Invasion of tumor cells into the surrounding connective tissue and blood vessels is a key
step in the metastatic spread of breast tumors. Although the presence of macrophages in …

Interleukin-1β (IL-1β) is a cytokine whose bioactivity is controlled by activation of the
inflammasome. However, in response to lipopolysaccharide, human monocytes secrete IL-1β …

Chicken hematopoietic cells transformed in vitro and in vivo by seven strains of replication-defective
avian leukemia viruses were assayed for the expression of six erythroid and five …

Platelets are generated from megakaryocytes (MKs) in mammalian bone marrow (BM) by
mechanisms that remain poorly understood. Here we describe the use of multiphoton intravital …

Pluripotent hematopoietic stem cells have been studied extensively, but the events that occur
during their differentiation remain largely uncharted. To develop a system that allows the …

The International Human Epigenome Consortium (IHEC) coordinates the generation of a
catalog of high-resolution reference epigenomes of major primary human cell types. The …