User profiles for Thomas Jungas

JUNGAS Thomas

CNRS-CBI-Toulouse 3 University
Verified email at univ-tlse3.fr
Cited by 1070

Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas …

O Yilmaz, T Jungas, P Verbeke… - Infection and immunity, 2004 - Am Soc Microbiol
Porphyromonas gingivalis, an important periodontal pathogen, infects primary gingival
epithelial cells (GECs). Despite the large number of bacteria that replicate inside the GECs, the …

[PDF][PDF] Inhibition of chlamydial infectious activity due to P2X7R-dependent phospholipase D activation

R Coutinho-Silva, L Stahl, MN Raymond, T Jungas… - Immunity, 2003 - cell.com
Chlamydia trachomatis survives within host cells by inhibiting fusion between Chlamydia
vacuoles and lysosomes. We show here that treatment of infected macrophages with ATP …

[HTML][HTML] Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane …

T Jungas, I Motta, F Duffieux, P Fanen, V Stoven… - Journal of Biological …, 2002 - ASBMB
Cystic fibrosis is characterized by chronic inflammation and an imbalance in the
concentrations of alveolar and lung oxidants and antioxidants, which result in cell damage. …

Ephrin B1 maintains apical adhesion of neural progenitors

…, A Béhar, P Tryoen-Tóth, JO Bush, T Jungas… - …, 2013 - journals.biologists.com
Apical neural progenitors are polarized cells for which the apical membrane is the site of cell-cell
and cell-extracellular matrix adhesion events that are essential for maintaining the …

Ephrin-B1 reverse signaling controls a posttranscriptional feedback mechanism via miR-124

DN Arvanitis, T Jungas, A Behar… - Molecular and cellular …, 2010 - Taylor & Francis
Eph receptors and ephrins exhibit complex and highly dynamic expression patterns during
embryonic development. In addition, changes in their expression levels are often associated …

[PDF][PDF] Cross talk between one-carbon metabolism, Eph signaling, and histone methylation promotes neural stem cell differentiation

MA Fawal, T Jungas, A Kischel, C Audouard… - Cell reports, 2018 - cell.com
Metabolic pathways, once seen as a mere consequence of cell states, have emerged as
active players in dictating different cellular events such as proliferation, self-renewal, and …

[PDF][PDF] Developmental upregulation of Ephrin-B1 silences Sema3C/Neuropilin-1 signaling during post-crossing navigation of corpus callosum axons

E Mire, M Hocine, E Bazellieres, T Jungas, A Davy… - Current Biology, 2018 - cell.com
The corpus callosum is the largest commissure in the brain, whose main function is to
ensure communication between homotopic regions of the cerebral cortex. During fetal …

[HTML][HTML] Inhibition of DHFR targets the self-renewing potential of brain tumor initiating cells

MA Fawal, T Jungas, A Davy - Cancer Letters, 2021 - Elsevier
Brain tumors are a heterogeneous group of benign and malignant tumors arising from the
brain parenchyma and its surrounding structures, with in general a poor clinical outcome due …

[HTML][HTML] Eph: ephrin-B1 forward signaling controls fasciculation of sensory and motor axons

M Luxey, T Jungas, J Laussu, C Audouard… - Developmental …, 2013 - Elsevier
Axon fasciculation is one of the processes controlling topographic innervation during embryonic
development. While axon guidance steers extending axons in the accurate direction, …

Cell death and inflammation during infection with the obligate intracellular pathogen, Chlamydia

JL Perfettini, V Hospital, L Stahl, T Jungas, P Verbeke… - Biochimie, 2003 - Elsevier
Infections by Chlamydia are followed by a strong inflammatory response, which is necessary
to eliminate the infection, but at the same time is responsible for the pathology of infection. …