In this paper, we extend the cubature Kalman filter (CKF) to deal with nonlinear state-space
models of the continuous-discrete kind. To be consistent with the literature, the resulting …

Cysteine plays a number of important roles in protecting the cell from oxidative damage
through its thiol functional group. These defensive functions are generally considered to be …

Nitric oxide (NO • ) competitively inhibits oxygen consumption by mitochondria at cytochrome
c oxidase and S-nitrosates thiol proteins. We developed mitochondria-targeted S-…

Spread options are a fundamental class of derivative contracts written on multiple assets and
are widely traded in a range of financial markets. There is a long history of approximation …

Mitochondria contain their own genomes that, unlike nuclear genomes, are inherited only in
the maternal line. Owing to a high mutation rate and low levels of recombination of …

Complex I has reactive thiols on its surface that interact with the mitochondrial glutathione
pool and are implicated in oxidative damage in many pathologies. However, the Cys residues …

Many proteins contain free thiols that can be modified by the reversible formation of mixed
disulfides with low-molecular-weight thiols through a process called S-thiolation. As the …

Reactive oxygen species (ROS) produced by the mitochondrial respiratory chain can be a
redox signal, but whether they affect mitochondrial function is unclear. Here we show that low …

This slim volume logs the development of a cascade of contagious ideas that has occupied
my space, time and mind in recent years. There was a clear triggering event that occurred in …

The S-nitrosation of mitochondrial proteins as a consequence of NO metabolism is of
physiological and pathological significance. We previously developed a MitoSNO (mitochondria-…