The antitumor efficacy of cancer immunotherapy can correlate with the presence of certain
bacterial species within the gut microbiome. However, many of the molecular mechanisms …

Known for nearly a century but through mechanisms that remain elusive, cells retain a memory
of inflammation that equips them to react quickly and broadly to diverse secondary stimuli…

With the advent of ChIP-seq multiplexing technologies and the subsequent increase in ChIP-seq
throughput, the development of working standards for the quality assessment of ChIP-…

Periodontal disease is more common in individuals with rheumatoid arthritis (RA) who have
detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal …

Cohesin and CTCF are major drivers of 3D genome organization, but their role in neurons
is still emerging. Here, we show a prominent role for cohesin in the expression of genes that …

Transcription corepressors are general regulators controlling the expression of genes involved
in multiple signaling pathways and developmental programs. Repression is mediated …

Insect societies are tightly integrated, complex biological systems in which group-level
properties arise from the interactions between individuals 1 , 2 , 3 – 4 . However, these …

Blood-feeding mosquitoes survive by feeding on nectar for metabolic energy but require a
blood meal to develop eggs. Aedes aegypti females must accurately discriminate blood and …

Modifications of histone proteins have essential roles in normal development and human
disease. Recognition of modified histones by ‘reader’ proteins is a key mechanism that …

Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying
molecular mechanisms have not been elucidated. To investigate the role of crosstalk …