User profiles for Thomas Sicheritz-Ponten

Thomas Sicheritz-Ponten

Professor in Computational Phage Biodiscovery, University of Copenhagen
Verified email at sund.ku.dk
Cited by 55527

Prediction of post‐translational glycosylation and phosphorylation of proteins from the amino acid sequence

N Blom, T SicheritzPontén, R Gupta… - …, 2004 - Wiley Online Library
Post‐translational modifications (PTMs) occur on almost all proteins analyzed to date. The
function of a modified protein is often strongly affected by these modifications and therefore …

Structure and content of the Entamoeba histolytica genome

…, E Tannich, M Leippe, T SicheritzPonten… - Advances in …, 2007 - Elsevier
The intestinal parasite Entamoeba histolytica is one of the first protists for which a draft genome
sequence has been published. Although the genome is still incomplete, it is unlikely that …

Enterotypes of the human gut microbiome

…, N Pons, J Poulain, J Qin, T Sicheritz-Ponten… - nature, 2011 - nature.com
Our knowledge of species and functional composition of the human gut microbiome is rapidly
increasing, but it is still based on very few cohorts and little is known about variation across …

[HTML][HTML] A human gut microbial gene catalogue established by metagenomic sequencing

…, HB Nielsen, E Pelletier, P Renault, T Sicheritz-Ponten… - nature, 2010 - nature.com
To understand the impact of gut microbes on human health and well-being it is crucial to
assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, …

Richness of human gut microbiome correlates with metabolic markers

…, K Kristiansen, P Renault, T Sicheritz-Ponten… - Nature, 2013 - nature.com
We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we
report the human gut microbial composition in a population sample of 123 non-obese and 169 …

Whole-genome analyses resolve early branches in the tree of life of modern birds

…, PF Campos, B Petersen, T Sicheritz-Ponten… - Science, 2014 - science.org
To better determine the history of modern birds, we performed a genome-scale phylogenetic
analysis of 48 species representing all orders of Neoaves using phylogenomic methods …

Environmental genes and genomes: understanding the differences and challenges in the approaches and software for their analyses

ML Zepeda Mendoza, T Sicheritz-Ponten… - Briefings in …, 2015 - academic.oup.com
DNA-based taxonomic and functional profiling is widely used for the characterization of
organismal communities across a rapidly increasing array of research areas that include the role …

The genome sequence of Rickettsia prowazekii and the origin of mitochondria

…, A Zomorodipour, JO Andersson, T Sicheritz-Pontén… - Nature, 1998 - nature.com
We describe here the complete genome sequence (1,111,523 base pairs) of the obligate
intracellular parasite Rickettsia prowazekii, the causative agent of epidemic typhus. This …

Multilocus sequence typing of total-genome-sequenced bacteria

…, RL Marvig, L Jelsbak, T Sicheritz-Pontén… - Journal of clinical …, 2012 - Am Soc Microbiol
Accurate strain identification is essential for anyone working with bacteria. For many species,
multilocus sequence typing (MLST) is considered the “gold standard” of typing, but it is …

Population genomics of bronze age Eurasia

…, V Zhitenev, L Orlando, T Sicheritz-Pontén… - Nature, 2015 - nature.com
The Bronze Age of Eurasia (around 3000–1000 BC) was a period of major cultural changes.
However, there is debate about whether these changes resulted from the circulation of …