Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion

DM Bannerman, T Bus, A Taylor, DJ Sanderson… - Nature …, 2012 - nature.com
Hippocampal NMDA receptors (NMDARs) and NMDAR-dependent synaptic plasticity are
widely considered crucial substrates of long-term spatial memory, although their precise role …

[PDF][PDF] An ER assembly line of AMPA-receptors controls excitatory neurotransmission and its plasticity

…, MK Kocylowski, A Brechet, G Zolles, T Bus… - Neuron, 2019 - cell.com
Excitatory neurotransmission and its activity-dependent plasticity are largely determined by
AMPA-receptors (AMPARs), ion channel complexes whose cell physiology is encoded by …

Forebrain-specific glutamate receptor B deletion impairs spatial memory but not hippocampal field long-term potentiation

…, T Celikel, Y Geng, B Schupp, T Bus… - Journal of …, 2006 - Soc Neuroscience
We demonstrate the fundamental importance of glutamate receptor B (GluR-B) containing
AMPA receptors in hippocampal function by analyzing mice with conditional GluR-B …

[HTML][HTML] Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

…, A Eltokhi, A Rozov, VN Chi, V Jensen, T Bus… - Communications …, 2021 - nature.com
The NMDA receptor-mediated Ca 2+ signaling during simultaneous pre- and postsynaptic
activity is critically involved in synaptic plasticity and thus has a key role in the nervous system…

Hippocampal NMDA receptors are important for behavioural inhibition but not for encoding associative spatial memories

AM Taylor, T Bus, R Sprengel… - … of the Royal …, 2014 - royalsocietypublishing.org
The idea that an NMDA receptor (NMDAR)-dependent long-term potentiation-like process
in the hippocampus is the neural substrate for associative spatial learning and memory has …

[HTML][HTML] Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors

DR Shimshek, T Bus, J Kim, A Mihaljevic, V Mack… - PLoS …, 2005 - journals.plos.org
Genetic perturbations of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs)
are widely used to dissect molecular mechanisms of sensory coding, learning, and …

[HTML][HTML] Deciphering the contributions of CRH receptors in the brain and pituitary to stress-induced inhibition of the reproductive axis

…, LC Roth, D García-González, T Bus… - Frontiers in Molecular …, 2018 - frontiersin.org
Based on pharmacological studies, corticotropin-releasing hormone (CRH) and its receptors
play a leading role in the inhibition of the hypothalamic–pituitary–gonadal (HPG) axis …

Impaired reproductive behavior by lack of GluR-B containing AMPA receptors but not of NMDA receptors in hypothalamic and septal neurons

DR Shimshek, T Bus, V Grinevich… - Molecular …, 2006 - academic.oup.com
The roles of ionotropic glutamate receptors in mammalian reproduction are unknown. We
therefore generated mice lacking a major subtype of (S)-α-amino-3-hydroxy-5-methyl-…

[HTML][HTML] AutonoMouse: High throughput operant conditioning reveals progressive impairment with graded olfactory bulb lesions

A Erskine, T Bus, JT Herb, AT Schaefer - PLoS One, 2019 - journals.plos.org
Operant conditioning is a crucial tool in neuroscience research for probing brain function.
While molecular, anatomical and even physiological techniques have seen radical increases …

[HTML][HTML] Different forms of AMPA receptor mediated LTP and their correlation to the spatial working memory formation

DR Shimshek, T Bus, B Schupp, V Jensen… - Frontiers in Molecular …, 2017 - frontiersin.org
Spatial working memory (SWM) and the classical, tetanus-induced long-term potentiation (LTP)
at hippocampal CA3/CA1 synapses are dependent on L-α-amino-3-hydroxy-5-…