User profiles for Tianchen Qian

Tianchen Qian

Assistant Professor of Statistics, University of California, Irvine
Verified email at uci.edu
Cited by 463

The microrandomized trial for developing digital interventions: Experimental design and data analysis considerations.

T Qian, AE Walton, LM Collins, P Klasnja… - Psychological …, 2022 - psycnet.apa.org
Just-in-time adaptive interventions (JITAIs) are time-varying adaptive interventions that use
frequent opportunities for the intervention to be adapted—weekly, daily, or even many times …

Sense2Stop: a micro-randomized trial using wearable sensors to optimize a just-in-time-adaptive stress management intervention for smoking relapse prevention

…, M Menictas, S Murphy, I Nahum-Shani, T Qian… - Contemporary Clinical …, 2021 - Elsevier
Background Relapse to smoking is commonly triggered by stress, but behavioral interventions
have shown only modest efficacy in preventing stress-related relapse. Continuous digital …

Estimating time-varying causal excursion effects in mobile health with binary outcomes

T Qian, H Yoo, P Klasnja, D Almirall, SA Murphy - Biometrika, 2021 - academic.oup.com
Advances in digital technology and wearables have made it possible to deliver behavioural
mobile health interventions to individuals in their everyday lives. Micro-randomized trials are …

[HTML][HTML] Linear mixed models with endogenous covariates: modeling sequential treatment effects with application to a mobile health study

T Qian, P Klasnja, SA Murphy - … science: a review journal of the …, 2020 - ncbi.nlm.nih.gov
Mobile health is a rapidly developing field in which behavioral treatments are delivered to
individuals via wearables or smartphones to facilitate health-related behavior change. Micro-…

[HTML][HTML] Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old

L Sordo, T Qian, SA Bukhari, KM Nguyen… - Acta …, 2023 - Springer
Hippocampal sclerosis of aging (HS-A) is a common age-related neuropathological lesion
characterized by neuronal loss and astrogliosis in subiculum and CA1 subfield of …

[HTML][HTML] Promoting Nrf2/Sirt3-dependent mitophagy suppresses apoptosis in nucleus pulposus cells and protects against intervertebral disc degeneration

S Hu, C Zhang, T Qian, Y Bai, L Chen, J Chen… - … medicine and cellular …, 2021 - hindawi.com
One of the causes of intervertebral disc degeneration (IVDD) is nucleus pulposus cell (NPC)
death, possibly apoptosis. In this study, we explored the role of the Nrf2/Sirt3 pathway and …

[HTML][HTML] How notifications affect engagement with a behavior change app: Results from a micro-randomized trial

L Bell, C Garnett, Y Bao, Z Cheng, T Qian… - JMIR mHealth and …, 2023 - mhealth.jmir.org
Background: Drink Less is a behavior change app to help higher-risk drinkers in the United
Kingdom reduce their alcohol consumption. The app includes a daily notification asking …

Baicalein Inhibits the IL-1β-Induced Inflammatory Response in Nucleus Pulposus Cells and Attenuates Disc Degeneration In vivo

H Jin, Q Wang, J Wu, X Han, T Qian, Z Zhang, J Wang… - Inflammation, 2019 - Springer
Intervertebral disc degeneration (IDD) is widely considered one of the main causes of low
back pain, which is a chronic progressive disease closely related to inflammation and …

[HTML][HTML] Resting-state brain information flow predicts cognitive flexibility in humans

OY Chén, H Cao, JM Reinen, T Qian, J Gou, H Phan… - Scientific reports, 2019 - nature.com
The human brain is a dynamic system, where communication between spatially distinct areas
facilitates complex cognitive functions and behaviors. How information transfers between …

Validation of the Hong Kong Liver Cancer Staging System in determining prognosis of the North American patients following intra-arterial therapy

…, J Chapiro, S Sahu, RE Schernthaner, T Qian… - Clinical …, 2017 - Elsevier
Background & Aims There is debate over the best way to stage hepatocellular carcinoma (HCC).
We attempted to validate the prognostic and clinical utility of the recently developed …