High intracranial pressure (ICP) can impede cerebral blood flow resulting in secondary injury
or death following severe stroke. Compensatory mechanisms include reduced cerebral …

Intracerebral hemorrhage (ICH) is a devastating stroke with many mechanisms of injury.
Edema worsens outcome and can lead to mortality after ICH. Glibenclamide (GLC), a …

Intracerebral hemorrhage (ICH) is a devastating insult with few effective treatments. Edema
and raised intracranial pressure contribute to poor outcome after ICH. Glibenclamide blocks …

As with ischemic and traumatic brain injury, raised intracranial pressure (ICP) is a common
life-threatening complication of intracerebral hemorrhage (ICH). Elevated ICP can lead to …

Intracerebral hemorrhage (ICH) is a devastating stroke often modelled in rats. Isoflurane
anesthetic, commonly used in preclinical research, affects general physiology (eg, blood …

Therapeutic hypothermia (TH) mitigates damage in ischemic stroke models. However, safer
and easier TH methods (eg, pharmacological) are needed to circumvent physical cooling …

Background The formation and degradation of an intracerebral hemorrhage causes
protracted cell death, and an extended window for intervention. Experimental studies find that …

BACKGROUND: After a large intracerebral hemorrhage (ICH), the hematoma and swelling
cause intracranial pressure (ICP) to increase, sometimes causing brain herniation and death. …

Patients with intracerebral hemorrhage (ICH) are at increased risk for major ischemic
cardiovascular and cerebrovascular events. However, the use of preventative antithrombotic …

Neural crest (NC) contributes to various structures of the eye including cornea, ciliary body
and retina. The association of NC-derived cells with hyaloid vessels in the form of pericytes is …